“I Wouldn’t Recommend It to Anyone”: What We Can Learn from Women who have had Bad Experiences with Depo-Provera

Depo provera
Depo Provera injection / Photo: Ciell (cc)
By Guest Contributor |

By Laura Wershler

Note from OBOS:  In 2009 and again in 2012, Our Bodies Ourselves posted two blog posts on the adverse effects and withdrawal symptoms that some women experience while using or quitting the birth control injection Depo-Provera. The posts generated thousands of comments from women who were having problems with the shot and were desperately seeking help and advice. OBOS invited Laura Wershler, a member of the Society for Menstrual Cycle Research and editor-in-chief of the society’s blog, to provide an update on what can be learned from the shared comments.

I am not a fan of the contraceptive injection Depot medroxyprogesterone acetate, broadly known as Depo-Provera. Response to two posts I wrote for the Society for Menstrual Cycle Research (SMCR) blog about the adverse effects women experience upon quitting this drug confirmed for me that Depo-Provera poses serious risks to women’s health and well-being that have not been adequately addressed by the sexual and reproductive health community. (Please note: I do not speak for the SMCR; my views are my own.)

Between April 4, 2012, when my post Coming off Depo-Provera can be a woman’s worst nightmare was published on the SMCR blog, and April 14, 2015, when comments closed to both this and a subsequent post, more than 1200 women left comments documenting their negative experiences. The second post was a Q&A with endocrinologist Dr. Jerilynn Prior from the University of British Columbia’s Centre for Ovulation and Menstrual Cycle Research, explaining the adverse effects and offering suggestions to manage the return to ovulatory menstruation. Our Bodies Ourselves also posted two blogs on problems with Depo-Provera: Questions About Side Effects of Stopping Depo-Provera (11/09/09) and Questions Remain About the Effects of Stopping Depo-Provera (3/29/12). The OBOS posts have received over 2000 comments.

In all of these thousands of comments, there were only a very few that shared positive experiences. Many more came from women who had no problems while taking Depo-Provera but were completely unprepared for the adverse effects they experienced upon stopping. As one woman wrote:

It has been one year since I first posted about my “positive” experience receiving my first AND LAST depo shot. I’ve been following these comments religiously and they have been very helpful. Thank you. Here’s how it went for me: Depo Provera was the WORST thing I ever did to my body.

Why do women stop Depo-Provera and what do they experience?

Women decide to stop Depo-Provera because of continual or erratic bleeding, mood issues, loss of sex drive, concern about bone health, loss of health insurance, desire to have a baby, or because, after taking it for 15 or 20 years, their doctors said they should.

Once they stopped taking Depo, many women found that these symptoms intensified and/or they started having new symptoms. The women who commented — from the United States, Canada, United Kingdom, New Zealand, Australia, and Africa — experienced heavy and continuous bleeding, extreme breast tenderness, weight gain, headaches, nausea, extreme mood swings, depression, hair loss, and damaged relationships. Some were frantic about delayed return to fertility, while others, fearful of being pregnant, had taken multiple pregnancy tests.

The short explanation for what they experience is hormonal chaos, an estrogen storm. Dr. Prior explains the endocrinology in the Q&A. Briefly, Depo-Provera suppresses a woman’s own hormones to near menopause levels. Post-Depo, the body works hard to regain reproductive function by overproducing estrogen. Because hypothalamic incoordination delays the return to ovulation, progesterone is not produced to counteract estrogen. Erratic, high, unopposed estrogen causes most of the miserable symptoms.

It was infuriating and heartbreaking to read how women of all ages — from 17 to 56, whether they had taken one shot or used Depo for two, seven, 15, or 22 years — had been adversely affected by these experiences. Some days I couldn’t bear to read another sad story or one more expression of regret. A common refrain was: If I had known then what I know now, I’d never have taken Depo.

To acknowledge and amplify the voices of the hundreds of women who shared their adverse experiences, I presented an analysis of their comments at the 21st Biennial Conference of the Society for Menstrual Cycle Research in Boston, MA, on June 4, 2015. As I said in my presentation, I believe the provision of Depo-Provera too often fails to honor informed choice or serve women’s health and well-being. I demonstrated this by sharing excerpts from the comments, organized under four main themes.

The Four Main Themes

Theme 1: Uninformed choice

In contraceptive decision-making, informed choice emphasizes that clients select the method that best satisfies their personal, reproductive, and health needs, based on a thorough understanding of their contraceptive options. To make an informed decision, women should also thoroughly understand the implications of using each method.

Comments suggest that although most women had some idea of the side effects they might experience while using Depo-Provera, they were not prepared for the physical and emotional impact of some of these side effects, and none were prepared for what they experienced after stopping.

It was a long seven months… mood swings, depression, tender breasts. I have the info I was given with the first shot, nowhere does it indicate the possible symptoms after quitting the shot.

I am a living nightmare and I feel constantly on edge. How can this injection be legal? I am from the UK and I wasn’t given any serious/rare side effects of this injection. I feel helpless!!!

I asked about side effects and was told they weren’t very prevalent and I may just have some spotting. I had the shot at the end of February 2013. I then proceeded to bleed, at times heavy to the point of gushing, until the middle of June. That is one hundred and sixteen consecutive days, nonstop.

This is terrible and I don’t understand why the facts were not clearly outlined for me. This is serious stuff I would have liked to have considered during my selection process, but was only really told about the benefits of depo and just the bone density side effect and altered cycle.

I now am regretting taking this shot because they warned me about the side [effects] while on the shot but never warned me about what would happen after.

One commenter said:

I read the possible side effects but no one ever takes those serio[u]sly.

Another was accusatory:

To the people who are blaming the doctors, don’t. It is YOUR responsibility to get facts and ask questions before starting a treatment … it does the job, it does what it’s supposed to, so please don’t complain about the minor side effects, rejoice because you did not get pregnant when you didn’t want to be.

The vast majority of women who commented did not consider their adverse effects to be minor, but rather responsible for diminishing their quality of life. One woman, after participating in the discussion, summed up what many of the commentators felt:

I reckon there is far too little information available about this shot, and it is given too freely without the side effects being clearly understood.

Theme 2: Lack of body literacy

Do most girls and women understand how their bodies work? Do most know how a healthy, ovulatory menstrual cycle unfolds? The answer is no. It is common for teenagers to start hormonal birth control before their reproductive system has matured and before they understand how it works.

As I’ve written in the past, when it comes to body literacy, we are not taught to “read” or understand our own bodies. On the contrary, we are taught to distrust our bodies and accept various artificial means to “manage” them.

Several commenters were prescribed Depo-Provera for menstrual problems such as irregular periods, heavy bleeding, PCOS, or endometriosis. This drug doesn’t cure any of these conditions but may reduce or eliminate difficult symptoms while a woman is using Depo-Provera. Unfortunately, the symptoms may resurface — and possibly increase — when the shot is stopped.

Some women are confused by that old birth control adage — the pill will regulate your cycle — not understanding that while the pill might regulate bleeding episodes, it does nothing to support return to ovulation.

I was on depo for seven years… I stopped in October and started on the pill because I wanted to try and regulate my period as fast as I could, because my husband and I decided to start a family.

And some gynecologists don’t seem to know how to help a young woman achieve fertility in the first place:

When I was 13, I had one dose of the Depo Provera shot and my period has not been normal since. I am now 19 and I can maybe count on two hands how many periods I’ve had in the last six, almost seven years. My gynecologist put me on the birth control pill about three years ago and told me it will run its course and my period will regulate itself, but that’s not the case. I stopped the pill about two years ago. I will bleed on and off from time to time, but it is more like spotting. I like to think my period is going to come and be normal, but it never does.

Many commenters talked about “getting Depo out of my system.” Three months after the last shot, the drug has left a woman’s system. Adverse effects are caused by high and erratic estrogen produced by her own body.

Will the bleeding ever stop? Is it just the depo working its way out of my body? Why is this occurring and will regular birth control daily pills help regulate the bleeding?

It just seems you have to play the waiting game for this stupid thing to get out of your system.

The mood swings were unbearable though. I had horrible fatigue and felt depressed all the time, like not wanting to go out or do anything. Also very tearful all the time. I went to the doctor and told her all my symptoms, she said I would have to wait for it to leave my system.

Theme 3: Feelings of fear, anger, regret, betrayal, and solidarity

It was hard for me to read and absorb, week after week, women’s emotional responses to their experiences with Depo-Provera.

They expressed fear:

Now I would like to go to a doctor and get a second opinion but right now I don’t have the money. I mean I’m really scared that the depo shot screwed me up so bad that I can’t have more children.

I don’t know when the bleeding is going to stop. I don’t know if I am going to go back to normal. I’m freaking out. Nervous. Scared. My fiance and I want another baby so bad. Nobody told me that the depo would do this. I will never take another BC ever again.

Here is what is killing me… I’m terrified that I am now infertile.

Anger was common:

The shot has been one of the worst things to happen to me and I’m so angry that I’m the one who decided to do this! It has [affected] the way I see myself as a mother.

I’m angry at the lack of education behind this inconspicuous injection. Had I known half of the stuff I know now I would never have walked into that room.

I’m angry that I ever accepted Depo into my body and now I’m angry to have to wean myself off. Is it heroin we’re talking about or birth control? I’m not looking forward to [the] next few months of getting Depo out of my system and finding a new birth control that isn’t made by corporate America. But I do appreciate this site and the information. Life could be worse but good luck if you think Depo is the bee’s knees.

Regret? Yes:

I am so not having fun and I think depo provera is the cruelest thing your doctor will convince you to do. Hate hate hate hate hate. Curse it to hell. I’d rather be pregnant six times over that go through this again.

I regret taking this shot and I feel like a complete idiot for doing it!!

Wish I never would’ve done that to my body. I’m so messed up because of this shot. I’m calling my doctor Monday. Yeah, the shot was 100% effective of preventing pregnancy. But honestly it’s not worth it! I would have rather gotten pregnant.

Women also spoke to each other in solidarity:

Who the hell put this drug on the market? Because I would very much like to put them on Depo Provera and see all the debilitating symptoms start affecting their work and personal life the way it has for all of us. I’m terrified of starting another birth control now.

No more hormones for me. The depo is a nightmare that I have yet to wake from. Think wisely my naive ladies. Be strong, my ladies in suffering. We suffer together, mostly in silence, but we are together and will win this battle. There is an end.

These comments also carry a sense of betrayal, in part a betrayal of their bodies, but also betrayal by the health-care providers who recommended or prescribed Depo-Provera and now can’t seem to help them understand or manage the adverse effects of stopping the drug.

Theme 4: Frustration with health-care providers

The second comment to my first post was from holistic reproductive health-care practitioner Amy Sedgwick:

It is amazing to me how often the repercussions of coming OFF hormonal drugs is overlooked by women’s doctors and how rarely women are forewarned of these issues.

It was obvious from women’s comments to the first post that most were getting little useful assistance from their doctors. This prompted the second post with Dr. Prior’s advice on how women might help their doctors help them. Dr. Prior and I both replied to many women, referring them back to the resources and information in that post.

How did commenters express their frustrations?

The doctors and specialists don’t have the answers, only a bill to pay on the way out of the door which just makes me feel even more sick!

I would never recommend this drug to anyone ever! The stupid doctors don’t tell you what the real facts and dangers are of this drug.

I was never told the facts by my GP that it may take up to two years to become pregnant after coming off depo provera. As a nurse I would say that it most certainly should have been the doctor’s responsibility to discuss this with me.

I went to the doctor about all my symptoms and it’s so sad how the doctor was saying it was not because of the depo when I never had these symptoms before.

The sad part is WOMEN have to go to blogs to figure out what’s going on because docs don’t give us the right info.

My ob, who administered the drug, doesn’t know a thing about my symptoms. Shouldn’t they know all the ins & outs of this drug?

To say it has been a nightmare is letting it off lightly, it has almost driven me insane, to the point of considering if life was even worth living. The ongoing breast pain, on and off swelling, sweating, insomnia, weight gain etc the list goes on. I went to specialists, doctors, family contraception centers and no one could help me.

What Can Be Done?

Are sexual health clinics anywhere doing a better job of serving women who have stopped Depo-Provera than the health care providers of the women who shared their stories? What can health care providers do better or differently to lessen the negative impacts of this contraceptive?

  1. Tell women exactly how Depo-Provera works and what to expect when they stop taking it. Tell them that their own hormone levels will become almost as low as in menopause and that upon stopping the drug they may experience extreme symptoms related to hormonal imbalance.
  2. Offer a Buyer Beware advisory for women considering Depo-Provera. In 2013, I took a contraceptive counselling course that used the book Managing Contraception on the Go by Mimi Zieman and Robert Hatcher. I found it interesting that the manual included a Buyer Beware advisory for only one contraceptive, Fertility Awareness Methods:
    The 5 "Rs" of Fertility Awareness
    If Fertility Awareness Methods require such a notice then why not the contraceptive shot? The five R’s of Depo-Provera would be:

      • Restrictions to sexual activity may occur due to continual bleeding, vaginal dryness and/or loss of sex drive.
      • Rigorous daily exercise may not limit weight gain.
      • Required high tolerance for quality-of-life threatening side effects.
      • Risk of pregnancy due to high discontinuation rate among users.
      • Risk of serious adverse effects upon stopping injections.

    Tell women up front, “If you hate it, come back and we’ll find another method that works for you.” A powerful drug requires powerful language.

  3. Use the information in Stopping Depo-Provera: Why and What to do About Adverse Effects to develop a treatment protocol. Every sexual health clinic or health-care practitioner who provides the contraceptive shot is obligated to educate themselves about adverse effects. Those who provide Depo-Provera must be the ones who support women through their post-Depo experiences, or they should refer women to someone who can.

If you can’t do 1, 2 and 3, consider whether you should be providing Depo-Provera to anyone.

What can we learn from women who share their bad experiences with Depo-Provera?

The contraceptive injection Depo-Provera is causing baffling, quality-of-life threatening adverse effects for many women. Their expressions of fear, anger, regret, and frustration must be heard, acknowledged, and acted upon. Women considering or prescribed Depo-Provera deserve concrete and comprehensive information about the effects they might experience both while taking Depo-Provera and after stopping it, as well as full support from their health care providers to understand and manage the return to regular ovulatory menstrual cycles. Providers unable to meet these criteria should not administer Depo-Provera.

We invite women to continue to share their experiences with Depo-Provera in the comments below.

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  1. Sara Sezun says:

    Given the dangers of hormonal birth control, why not just encourage more use of condoms? They’re still the safest contraceptive method.
    Given conventional medicine can’t seem to help women who used Dapo-Provera, maybe women should try other modalities, such as acupuncture or homeopathy.

    • OBOS says:

      All hormonal methods of birth control aren’t the same, and despite problems with some, most are considered very safe, and can have health benefits. A great site to find out about the pros and cons of all birth control methods is Bedsider, https://bedsider.org/.

    • Is says:

      Some of us have periods that make our lives a living hell, we want to get rid of them altogether. The pill made me a raging psychopath, the coil made me bleed non-stop for 6 months then I tried Depo, I don’t have periods or migraines anymore (past 5 years) and there has been no weight gain to speak of. I had several jobs severely impacted because I was “making it up” that I had period cramps, because I only just complained of that two weeks ago. For a while there my period was every two weeks or sometimes there were gaps of a couple of months here and there. When I started having hormonal migraines (every day for two weeks at one point) was my breaking point. My employer was awful with me, they had decided to get rid of me at the first chance they could get, I was treated like I was lying all the time. I would have much rather been at work than going through that hell. Starting this shot has given me the freedom to live a life without regular bouts of agony. No, I haven’t come off it yet, but I’m in my thirties and still never felt a maternal urge, I doubt the problems faced by some of these women is going to be my problem. If there’s depression to deal with I’m a seasoned pro at that I have a solid history of depression and anxiety since long before I started the shot. I’ve looked into all of the options time and time again over the years and for every form of female contraceptive there are people who love it and there are horror stories. This shot has made my life much better than it was before I started it.

  2. Shari Ritter says:

    I volunteered for DES action in Canada for many years . With a group of advocates we met with the Minister of Health Jake Epp, it was not approved then but then approved 20 yrs later.

    Now I have another women’s issue: please review literature on the deleterious consequences of fossamax/ biphosphnates . There are two class action suits, one in us and one in Canada- patrons todos of the jaw and spontaneous femur fractures.
    I fractured my humerus 6 mths ago and still not healed. Ortho surgeon agrees that it may be due to biphosphnates sitting in my bone preventing bone growth and I am DES exposed and took fossamax for 12 yrs

    • OBOS says:

      Thanks Shari. And yes, while we have been following the adverse effects of bisphosphonates some (see bit.ly/OBOSBisphosphonate) but definitely need to look into the latest research — will put it on the list!

  3. Marie Onerheim says:

    Contraception when you are fertile and the “bio identical hormones” after menopause. Women have been subjected to a widespread experiment on their bodies. Men would not tolerate it.

  4. Carrie Lynne Rounds says:

    After 20 years as a sexual health education specialist, sharing knowledge with young women about their bodies and all birth control options, including the risks of using depo, I chose this option to relieve severe cramping and just received my second shot. I’m 49 years old, not in menopause yet, and for the past 20 years since getting off the pill I suffer extreme, debilitating cramps every 28 days. I’ve gotten a uterine ablation, checked for endometriosis, and still suffered three days out of each month with pain that no meds could relieve. The options presented to me were either hysterectomy or Depo. I feel like I betrayed my education and my body but I couldn’t suffer anymore. So far the side effects for me are mood changes and breast tenderness but I’m not cramping anymore so I consider it a trade off. The plan is to leave me on depo until menopause takes care of my cramps but now I wonder how I will even know when that is and how am I going to feel when I stop.

    • Laura Wershler says:

      Hi Carrie Lynne, Thank you for sharing your experience. It’s unfortunate you’ve found no pain relief over the last two decades. If Depo-Provera gives you some relief, then it may be worth it, even without answers to the questions you pose about the future.

    • Dawn williams says:

      New warning on depo you should not be on it for more than 2years. They kept me on this horrible drug for 9 1/2 years it has left me on permanent disability. And osteoporosis. I am also on prozac to help with the anxiety and depression.

      • wendy maggs says:

        hi dawn my daughter has been on this depo for almost 20 years in between having a family, NOW at 35 she has arthritis depression real bad mood swings, and now possibly osteoporosis which is one of the side affects of this drug, surely this cant be allowed inflicting pain and depression on others? my daughters life is a mess can i do anything about this?

    • Rose says:

      Hi Carrie,
      It has been a couple of years now-can you tell me how this treatment has been going for you-as I am in the same boat. But I’m not sure if I want to do this shot as I’m 47 and I’m a hormonal mess already.

  5. Kassie says:

    I am 18 and I quit the depo 2 days ago and I am terrified I am already feeling pain! I can tell that I did not do the right thing by getting the depo, my family has said this is just the start, well I don’t want to see what is coming in the future for me, I just feel like crying honestly, I was only told about the benefits, what they failed to mention is that I would gain weight(aka 20 to 30 lbs), I think that this drug should be banned all across the world!

  6. Brandy says:

    This shot has ruined my life for 18 years!! I’m sick (feel like I have morning sickness during my ovulation & period) 26 days out of the month. I have been diagnosed with pms and pmdd, Drs just keep wanting to put me on antidepressants!! The only thing that makes everything depressed is how sick my hormones make me!! I NEVER did this before the shot. I’m at the point of wanting to commit suicide because I still have at least 12 more years to go before I hit menopause & I no longer have a life, I just exist. I sit at my home & watch others living their lives on Facebook or tv and I break down in tears!! I wish I knew the dangers before taking it but my dr said there were no bad side effects.

    • Kelsey says:

      If you don’t want to take antidepressants than eat food with seratonin and find ways to help naturally. Also take B6 and B12 vitamins. You may also have had underlying depression. It may not just be the shot

      • Dee. says:

        This response is to Kelsey. Number 1 you cannot eat certain foods to avoid an antidepressant. You can try to get help naturally,sorry in my opinion you are wrong,wrong,wrong. Plus no vitamins will help. I have been through hell and back. Please dont tell someone they might of already had underlying depression. The depo shot is just awful please whoever asked about this and got Kelsey’s thoughts….please go to your professional and lay it all out on the table. Be informed by them and do research for yourself. Im far from a no it all but i have lived it. Everyone is allowed to give their own opinion but really did you ever stop to think some people could read certain comments and say yah they may be right and go down a path of hell pure torture. Please everyone it helps sometimes and gives us all comfort in hearing about others peoples stories. However please get informed yourself and do whatever it takes to see what is best for every individual. I just got really upset with Kelsey saying that stuff. It was like a smack in my face and i am sure to others on here also. But hey believe and do what you want,you are gonna end up playing with fire. I am not telling anyone yah just go on antidepressants. What i am saying is give your story or opinion. All us girls or woman should stick together. Find out what is best for each of us as strong females in which all our bodies are different from each others. God bless and take care.

  7. Alegra L., Health Coach says:

    I am one more case of regretting depo-provera. I was an uninformed high schooler in the 90s who wanted to “forget about my period” as a benefit to birth control. I had one and only one shot. Increased pain when I was supposed to be menstruating & extreme emotions are what I remember. What a mistake!

  8. Callan says:

    I have one more month until this shot wears off and honestly I’m praying I make it.i have no idea what to do about the side effects I’m experiencing. I have absolutely NO appetite…I feel as though I am anorexic and being as I had a baby just four months ago I’m scared I might lose the weight too fast and ruin my body. Also I cannot stop snapping at my husband Im not even sure if he wants to be with me after these two months,I’m not being dramatic it’s THAT BAD. Not to mention my poor daughter is only five and like I said the other one is four months and I find myself SCREAMING at them because I cannot control my emotions. Then I go lock myself in my room because I feel that’s better than flipping out on everyone I feel like a terrible wife and mother and iv had depression in my teenage years so I know that it is returning.Iv asked myself several times how I’m gunna make it I’m weak, nauseous, I have so much diarrhea that I have diaper rash from using the bathroom so frequently. So far iv been bleeding for two weeks…I feel as though I’m slowly being poisoned and there is nothing I can do about it iv called my doctor three times and he never had any answeres as to how to help I just want HELP I don’t wanna be this person I absolutly hate my life I dread going to sleep because when I wake up I am dripping sweat and freezing. The first two hours of my day every day I feel like I drank battery acid my stomach feels like it is eating itself I make myself eat but I gag the whole time. Eating has never been a problem for me iv always taken great care of myself so I have to say this is one of the biggest regrets of my life.

    • Jessica says:

      Dear Callan,

      I have only just come across this now and I am sorry to hear your story. I just want you to know that Jesus loves you and you are precious in his eyes. You may feel like your world is falling apart but He is there by your side. He can bring healing to your body. Call out to Him and ask him to reveal Himself to you. God bless you and I hope you find your peace in him.

    • Shauna says:

      I started the depo at the age of 18yrs old. At the age of 29 I stop taking it!
      The after effect is the worst Headache, depression, low sex drive
      Heavy cramps & Cyst just terrible!! Didn’t think trying to protect myself wold have cause me harm. Another lesson learn

      • SJ says:

        I have been on the Depo off and on for 20+ years and based on the fact that it’s not recommended for long periods of time as stated in their info, it’s a must to check into. Personally, I haven’t had any menstrual/physical/emotional problems but that’s my particular situation (off and on it 3 times now since 1995, including months and year’s of breaks). I know it states that one shouldn’t be on it for more than a few years at a time at most which let’s your body return to it’s normal state. I’ve never had any repercussions of being on the shot but you must research yourself before getting on any kind of BC in general.

    • Maryan says:

      I am the same. This is the biggest mistake I ever made. I was a nice girl, going to school, working, having a very good relationship with my coworkers, I was A student. After I took the shot, everything changed. I started fighting with people, I ruined my grades, I got depression, and nobody was around to help me. I don’t know how it’s still legal? How? Maybe thousands of women suicid, as I was going through it, and no one ever realized that it was because of this freaking shot. It’s sad that I lost my happiness, and my life over just one mistake.

    • Louise says:

      How are you feeling now callan?
      I have also had the Depo, it ran out 3 weeks ago and I feel everything you felt. I really hope you’re better

  9. Andrea says:

    Everyone that’s written about a bad experience, I’m experiencing it right now. I literally feel my life falling apart. When does it end ?!??? Serious question 🙁

  10. J-to says:

    I’ve taken it on and off for 8 years; I was an bottomed out alcoholic for several years and felt a little bit safer that I was less likely to bring a helpless child into the world with FAS.

  11. Amber says:

    I was on Depo for almost 10 years. During the time, I was on it. I never had any issues. However, I decided to stop so I can start a family. Now, I have increased anxiety and moodiness. My breast are extremely tender, I usually get a week or so off, where they feel normal. Been almost 4 months since I stopped and still haven’t had a cycle. I believed Depo was a great shot when I was on it, but now I have buyers remorse at using it. My doctor has nothing to say other than, it my issues could be hormone surges and some women have taken as long as 18 months to get back to normal. If this is the case, then why do they immediately go to this option for women?

  12. Ashley says:

    23 months ago I took the depo shot and only one. Since then I have had irregular periods ever sine until now. Last night my husband and I had intercourse and I woke up this morning covered in blood and I have been bleeding heavy all day. The cramps are strong and painful. I have had six children in the last 11 years and my husband and I have been trying to conceive another. Never had trouble before. I think its the depo shot. But why now ? Why so heavy? So painful.

  13. Valerie DeWitt says:

    My advice to anyone considering taking Depo and/or anyone considering quitting: BEWARE.

    In my teens and early 20s my period was so painful, with cramps and back aches that left me with tears in my eyes, nauseous on the floor, praying for it to pass. When I was younger I took the pill, but hated the discipline and management needed to take a daily pill at the same time everyday, and I was worried about weight gain.

    Around 20 or 21 years old I began taking Depo, with the only precaution being “possible bone loss” described to me as something I would encounter way, WAY, in the future, and, hey! I could take a caramel-flavored chew for that (as simple a response as “hey, there’s an app for that!”) so I barely batted an eye when getting on board with depo.

    No daily pills? Check. No periods? Check. No cramps and awful back pains? Check. No pregnancy on top of all those perks?? Check! Count me in. AND, not likely I’d gain weight?! Oh, hell yeah!!! Sign me up!!!

    Now, don’t get me wrong, my experience ON depo was great, and all those things I just “checked” off? Yep, I enjoyed them. But, OFF depo? If I had it to do again, never would I EVER have taken it.

    January of this year (2016) I got my last depo shot. I had new insurance and therefore a new doctor, and after finding out I’d been on depo for well over 7 years, she said she’d give me one last shot and then I needed to decide on a new birth control. She was not comfortable issuing me more than one last dose as it appeared I may have been on depo as long as or longer than 10 years.

    At the time I wasn’t seeing anyone and thought my body may deserve a break so why not go off it for a while? If I get back to having an intimate relationship maybe I could try an IUD like she suggested. I had no idea what was to come.

    At the time of my last shot (Jan ’16), I already felt overweight, not for my height I guess but for my normal body – 5’6″ and 145 lbs. Now, October ’16, 6 months since the medicine “should’ve” started wearing off, I’m 163. I had to buy new clothes. I feel like a stuffed sausage. Worse than the weight though, through the spring months I encountered the worst depression I have EVER encountered, thinking every day was my last because I dreamed, fantasized even, about taking my own life on the regular – I have never experienced a sadness like this, the sadness can’t be put into words. Thank god for Prozac. Ugh.

    Shoot forward to now, I haven’t changed my eating patterns or exercise patterns compared to that of when before I gained this nearly 20 pounds in just a few short months, if anything i eat less, yet I still continue to gain weight. I’m exhausted. My boobs hurt so bad and nipples are so hard all the time I feel like I should audition for a porn. It’s literally painful to touch then anytime, a shower hurts, and taking my bra off and slipping even the comfiest shirt/tank on at the end of the day kills. It’s ridiculous.

    My new doctor said I’m likely ovulating, but had no projection as to when I may get my period back; I hurt, I’m uncomfortable, and I’m sick of this “ish.”

    If anyone has something they recommend instead of depo I’m all ears ! Hopefully I helped some woman with my story. Best of luck!!!

  14. Valerie DeWitt says:

    My advice to anyone considering taking Depo and/or anyone considering quitting: BEWARE.

    In my teens and early 20s my period was so painful, with cramps and back aches that left me with tears in my eyes, nauseous on the floor, praying for it to pass. When I was younger I took the pill, but hated the discipline and management needed to take a daily pill at the same time everyday, and I was worried about weight gain.

    Around 20 or 21 years old I began taking Depo, with the only precaution being “possible bone loss” described to me as something I would encounter way, WAY, in the future, and, hey! I could take a caramel-flavored chew for that (as simple a response as “hey, there’s an app for that!”) so I barely batted an eye when getting on board with depo.

    No daily pills? Check. No periods? Check. No cramps and awful back pains? Check. No pregnancy on top of all those perks?? Check! Count me in. AND, not likely I’d gain weight?! Oh, hell yeah!!! Sign me up!!!

    Now, don’t get me wrong, my experience ON depo was great, and all those things I just “checked” off? Yep, I enjoyed them. But, OFF depo? If I had it to do again, never would I EVER have taken it.

    January of this year (2016) I got my last depo shot. I had new insurance and therefore a new doctor, and after finding out I’d been on depo for well over 7 years, she said she’d give me one last shot and then I needed to decide on a new birth control. She was not comfortable issuing me more than one last dose as it appeared I may have been on depo as long as or longer than 10 years.

    At the time I wasn’t seeing anyone and thought my body may deserve a break so why not go off it for a while? If I get back to having an intimate relationship maybe I could try an IUD like she suggested. I had no idea what was to come.

    At the time of my last shot (Jan ’16), I already felt overweight, not for my height I guess but for my normal body – 5’6″ and 145 lbs. Now, October ’16, 6 months since the medicine “should’ve” started wearing off, I’m 163. I had to buy new clothes. I feel like a stuffed sausage. Worse than the weight though, through the spring months I encountered the worst depression I have EVER encountered, thinking every day was my last because I dreamed, fantasized even, about taking my own life on the regular – I have never experienced a sadness like this, the sadness can’t be put into words. Thank god for Prozac. Ugh.

    Shoot forward to now, I haven’t changed my eating patterns or exercise patterns compared to that of when before I gained this nearly 20 pounds in just a few short months, if anything i eat less, yet I still continue to gain weight. I’m exhausted. My boobs hurt so bad and nipples are so hard all the time I feel like I should audition for a porn. It’s literally painful to touch them anytime, a shower hurts, and taking my bra off and slipping even the comfiest shirt/tank on at the end of the day kills. It’s ridiculous.

    My new doctor said I’m likely ovulating, but had no projection as to when I may get my period back; I hurt, I’m uncomfortable, and I’m sick of this “ish.”

    If anyone has something they recommend instead of depo I’m all ears! Hopefully I helped some woman with my story. Best of luck!!!

    • Jo says:

      CONDOMS darlin’ when you have the energy…no matter how desperate you get have faith that ur body is a very complex but strong piece of machinery and when it’s had enough it will shut down and allow you to sleep like sleepin beauty. You may look young,nobody will see how you suffer but my god the body will feel ancient!!!! And hey you’ve jogged my memory of things that arnt normal but have become the norm. Chin up sweet cheeks x

  15. Jo says:


    A little about myself and backgroud : At age 19 after my son was born I took a contraceptive pill. I felt a bit moody so after my initial 3 months supply I decided not to bother…being married it didn’t matter if I fell pregnant or not. At 39 I had a change in circumstance and at age 40 I decided I should think about contraception… as I wasn’t in the routine of popping a pill everyday I thought I would probably forget and I didn’t fancy a coil but I’d heard about this injection that lasted 12 weeks so I thought this was probably my best option.
    I wasnt given any information apart from I may put on weight….on first injection my periods stopped and I thought WOW this is a godsend and I put on 2 pounds.

    I have questioned over the years could it of been the injection or could it have been a 12 week course of smoking patches??? (they were the only 2 things in my system in a 4 year period that had never been there all my life). I don’t wish to scare or put anybody off a choice they wish to make about contraception after all “it is better to be safe than sorry” and like everything what is “good for one can be rubbish for another” and I’ve always been a “i’ll do what I want it’s my life” kinda person as well haha.

    Now I may get a bit confused with events or timing here as in 2009 9 months after bloods after bloods after bloods all came back CLEAR I diagnosed with CHRONIC FATIGUE SYNDROME which they thort I’d had since 08 but looking back at old pics I think my problems were there in 06 which was 2 years into the injections.

    If started with feeling quite tired and lower back pain, I eventually gave in and went to my GP I had blood tests ALL CLEAR nothing wrong with me.
    I suffered the pain and within 6 months it progressed to what I wouldnt call a headache just a dull ache on the left side of my head which lasted approx 15 mins with a feeling of being very ditzy if not somewhat brain dead, the backache got worse I put on 10lbs in 1 week,my stomach n boobs swelled I looked pregnant but my I had a fantastic set of “double D” boobs for my petite frame :)…so a year after initially going to see my GP I was back to see my GP again she sent me to hospital I had cysts on liver and kidneys…I suffered more pain, I felt more tired and more ditzy then the weight started to drop off me I went back to hospital to get my cysts checked they hadnt disappeared but they hadn’t grown either! LUCKY ME!!!
    I carried on working, I carried on feeling quite ill but I decided not to get the injection again something was causing this and if the injection then surely things would get better.. NO THINGS DIDN’T GET BETTER IT WAS A DOWNWARD SPIRAL!!!!

    I was in agongy, all I wanted to do was sleep, my energy was so low and I had to leave a job I loved and apart from a 6 month bleed 18 months after stopping the injection my periods to date (im probably thro the change of life now) never returned but I never fell pregnant having unprotected sex…hmm if that’s what you could now call it lying there like log not a human!!!!…
    I’d had my family and I didn’t want anymore so for me it didn’t matter if my periods didn’t return but for young people be careful, at 45 tho I would of liked my health back and be the whippet not the snail I’d become.

    I’ve been to hell and back not once but for the last 7 years, I’ve spent 20 hours in a 24 period sleeping, I’ve been stuck in bed for weeks on end, pain has been unbearable as I’ve aquired an intolerance to meds (apart from being able to take 1 over the counter anti nflam no more than 3 times a day and for no more than 3 days…they have become what I call my emergency med’s when I can’t stand anymore) energy levels so low I could hardly feed myself or walk, problems with eyesight, cognitive problems, I’ve had to move into a smaller flat and iv been stuck in the house like a damned recluse since I left work in 09.

    Diagnosed with CFS nothing GP can do for me unless I want anti depressants which have good side effects of insomnia and energy (I tried.. they gave insomnia but did nothing for energy and within 10 mins of taking I cried solid…3 weeks of “the not so HAPPY tablets” took 3 months to get out my system and for my “own humour” to return and get me thro this) also don’t think for one moment it’s been a simple process as a single person having to give up work and diagnosed with CFS claiming UK benefits… FAR FROM IT looked on as a maliger all in the head…I manage on what I get coz I don’t have a LIFE outside of HOME but it doesn’t allow to make my life any easier!
    Can I blame my GP probably not he may not of had all info to hand at the time but some counties have got lawsuits with this pharm comp so who in UK is gonna take up lawsuits for us…they could make a fortune form us less fortunate!!!
    I feel like I’ve been a test dummy to shorten my life and I won’t bow down to more med’s unless I’m dying!!!!!
    It’s taken me at least four hours to write this…PLEASE young girls and young mothers THINK TWICE xx

  16. Tina says:

    Ruined important friendships, made me emotionally unstable, and I attempted to commit suicide the day after my birthday. Yeah, I highly recommend staying away. I read the possibility of depression and increased anxiety level. I made myself aware of the possible side effects. No amount of research could have prepared me for the most difficult 3 months of my life. Seriously, if you think you’ve done enough research and still want to get the depo shot…DO NOT GET IT. Trust me. You do not want to deal with the repercussions. Stick with condoms or regular birth control pills.

  17. Nikki Cunnigham says:

    I was wondering does the depo have anything like the antidpressant properties. Somewhere I read it did. I have bipolar and can’t tolerate any type of antidepressants. I have had three shots and now and it finally stopped my months of bleeding. Although my bipolar was stable and having issues now. Also when I take the shot around week two it make me itch and go numb especially around the mouth. I can deal with it with benadryl but is that safe?

  18. Vanessa says:

    My question is, is there a treatment for any of this? Does it get better? So many people have commented that the symptoms of withdrawal are real, but there is no feedback on treatment or recovery. I had my last injection in February 2016. I was fine the entire time I was on it. Starting in the summer I began having Panic Attacks, Depression, Insomnia, Headaches, Nausea, Leg Pain, Muscle Weakness, you name it. I had my hormone levels drawn and on paper I seem menopausal, but I’m only 29. I’ve seen 2 OBGYN who dismiss the issue, and tried to get in with Endocrinologist, but they said they do not treat hormones. Tomorrow I’m going to see a BioIdentical Hormone Doctor in hopes they can calm the side effects. Has anyone else had these body pains and muscle weakness, and does anyone have any answers. Please?

    • Jo says:

      I have read after 3 years of using that bone loss (osteoporosis) is comparable to that seen in women going through menopause and within 30 months of stopping bone levels return….I would think bone loss could cause pain so could bone returning to normal also be the cause of pain x

      While on the depo did anybody notice if they grew in height… I grew an inch within first year,after coming off the depo I shrunk 2 inches and now i’m back to my orginal height…hmmm!!!!

    • Yas says:

      I’m so sorry that you’re experiencing this but I’m going through some of the same things. I’m 28 and I got my first injection in February of this year also. I only had one more injection in May and bled the whole time so I decided that the May injection would be the last. By June, the bleeding had stopped but there is a strong odor coming from down there, especially after sex. I have a six year old so I know what it feels like to be pregnant and that is exactly how I feel. I get nauseous constantly, my back hurts, my breasts feel engorged, and I feel so weak. I’ve taken numerous pregnancy tests over the span of two months, all negative. I feel insane. I barely sleep. I haven’t gone back to my OBGYN for them to assess anything but as selfish as this is, I’m happy I’m not alone. Well wishes to you and your recovery. I hope we make it out of this nightmare soon.

    • Yolette Inskip says:

      Search for “A Wake-up Call about Depo Prevera” on the internet. This letter explains in detail how the injection can cause chronic backache and render one handicapped as a result of pain. I am in a similar boat. After my third injection my lumbar vertebrae area is almost in continual pain. I cannot walk the dog, cycle or participate in my much loved aerobic classes at the moment. I have been reduced to moving in the pool on a noodle just over a period of a month. The pool, however, is proving to be my saving grace as being weightless in water allows me to run, walk and jump in the pool, all exercises that strengthen essential lower back muscles weakened by depot prevera.

  19. KG says:

    I am 2 and a half months in to my first shot and I had no idea I could experience so many side effects, the worst of it is night sweats, waking up 2-4 times a night, trouble sleeping, non stop spotting (for over 2 months now), no sex drive, and mood swings. I was not informed properly of the side effects and told that at most I would probably just experience spotting. This is definitely the worst thing I have ever done to my body. I am barely functioning with the lack of sleep, it has affected my work, my relationship, I don’t even feel like myself anymore. I am scared to find out what the withdrawal effects might be. Is there some way to report side effects so that the FDA has a better understanding of how many women are affected by this drug?

  20. Steph says:

    I was using seasonique (which I loved) but had painful “mini periods” if I skipped even 1 pill. I was told depot shot would be a good option and there could be some unpleasant side effects like weight gain but to not worry because they’re “pretty rare.” 1 day after my 1 and only shot, I had woke up with an EXCRUCIATING headache, major joint pain, severe depression…No period or spotting at all. Exactly 1 year later I had my first period (usual, normal, no problems) then 2 weeks later got it again and it hasn’t stopped since. Every single day since the first week of September I’ve had a constant flow and terrible ovarian pain. PCP has referred to check for PCOS but appointment is next week. Last week it changed to a really heavy, cramping period and hasn’t let up at all. Biggest regret of my life was getting that one shot. The OB/GYN that gave it to me even told me that it’s probably not what was causing my terrible headaches or other symptoms!!!

  21. Veronica de Oliveira says:

    I’ve taken the injection in June, so it suppost to be out of my body by now. But now I’m experiencing horrible Brest pain, mood changes, nausea… just like I’m pregnant, besides the fact that I just friked out thinking I was! Not right! It should be banned!

  22. Cayla says:

    I started the depo shot in June/July of 2015 due to being on the pill and getting pregnant. That ended in a miscarriage and I decided to try a new method. I wanted to try this because after talking to friends and several other people from work, they had successful and positive stories of their experiences. The last shot I received was in January 2016. From the time I started the injection up until now, Dec. 2016, I have bled countless amount of times. From having my “period” for two months, and off for maybe a week then bleed another two months, not having a period for 6-8 weeks and having the pregnancy scare, and so on, I regret ever taking this medication.
    I’ve gone to my doctor about the uprising issue and what did she do? Absolutely nothing! I always got, “just wait it out”, “it’ll stop on its own”, “I don’t know exactly what you mean by the issues, let’s run some labs and other tests.”
    To going to a specialist and getting put back on the pill to regulate me. Always a run around.
    My horomones are ridiculous. Mood swing after mood swing. Anywhere from thinking my boyfriend is the best person in the universe, to wanting to ball my eyes out over the stupidest things, then to wanting to kill every living thing I seen. I yell and scream at my dog, boyfriend, parents, family and friends over the dumbest of things. Then I cry my eyes out over my boyfriend forgetting my order wrong at the drive thru. Never in my life have I ever been like this. I just wish it would end already! Almost a year from my last shot and every time “Aunt Flo” comes for a visit, I think I’m starting to become regular. Jokes on me. I started my period around 11/15/16 and ended on 11/20/16. Everything was fine then I went to the bathroom and wiped only to see a few spots of blood on 11/28/16 and have been on and off bleeding since.
    I will never take the depo provera injection again and I will let others know my story of experience if they tell me they want to try it. I would never recommend this and I wouldn’t wish it upon my worst enemy.
    I wish this all would end.

  23. Aj says:

    I was on the depo shot for 2 years then I had stopped I had no symptoms at the time. I got pregnant 6 months later with my son! After having my son I had got the depo shot again, now my bones (joints) hurt all the time (knees, wrists) I have lost a lot of my hair it use to be full and now it’s so thin! I also have lost my sex drive 🙁 I wish I would of never got this shot! The only thing it did for me was help me with my skin disease! Other than that it was a horrible decision!

  24. Vickie says:

    I agree that doctors should have to tell people the side effects of being on depo and stopping it. After experiencing difficulty breathing, chest pain, heart palpitations and other scary symptoms, I went to a doctor – she told me I am breathing wrong, that it is my fault even though this never happened before depo, that there is nothing that can be done to help me and no medication for it…..worst birth control ever! I hope they stop giving it

  25. zurysadai says:

    i had a question i haven’t really experienced some of the situations that has been posted but i am scared i could start experiencing them.. i started the depo-provera right after i gaved birth my doctor said it was the surest thing i could take while i was on the shot i had irregularly periods i would only spot from time to time also i had huge headaches.. me and my husband decided to have another baby so i stopped getting the shot i only took the shot four times and my period hasn’t got normal until last month i was bleeding heavily and i would stain everything that i would wear or sit on but i thought it was regular i thought it was my period getting back to normal it lasted seven days then i got it again the same month and it was heavy again i have concerns if it will get worse or is it something i shouldn’t worry about??

  26. Stephanie says:

    I am also in this camp of anger, regret, and uninformed choice regarding depo. My story is dead similar to the others you’ve noted above. I only did three rounds of shots and I’ve been off it for a year and for four months now, have been getting periods every 12-15 days. Not ovulating, diagnosed with PCOS, gained 20 pounds, mood and depression struggles…all the things. This stuff should be ILLEGAL. I wish there was a class action lawsuit or something I could join to get this off the market. And, it seems you have to google the exact right phrase to find any articles like this to confirm the symptoms and that I’m not a lunatic!

  27. Andrea says:

    I got this shot 3months ago. And I’ve had all the adverse effects since then. Especially the irregular bleeding. It really kills me. I don’t know what is gonna happen when quit the shots. I am so scared. Is there any way that can stop bleeding and back to my normal cycle?

  28. Dawn Foster says:

    I had Depo for contraception for over 20 years and my periods stopped completely.I was advised by my Dr to stop using it because of the health risks due to my age ( 50). Since then,over a year later,I still haven’t had a period and have lost 17 kgs which has now put me underweight at 55kgs.Has anyone else had unexplained weight loss??

    • Edith says:

      I have to say, I am surprised your Dr. Let you take the shot for so long. When I began the shot when it first came out in 2000 , my Dr. Stated you can only take the shot for up to 5yrs then you must get off it to give your body a rest. I am 48 I have been off the shot for 8 yrs. I preferred to have my tubes CLAMPED to avoid the reoccurring adverse effects of the DEPO Shot which has worked very well for me. No pregnancy in 4ys since I had my tubes CLAMPED. No cut, not tied or burnt.

  29. Susie says:

    I have been getting the shot for 12 years; I am getting ready to stop. I would say for the most part I have been very happy with the results. Only within the last few years have I had negative side-effects (extreme dryness is the worst). As I am reading through the post shot side-effects I am scared as heck what might happen. I am in my mid 40’s and there is a good chance I am not “ready” to go through my change of life just yet (unfortunately). Wish me luck, hopefully I will lose the 15 pounds I have gained over the past 12 years and won’t be too awful to my family!

  30. odehlia says:

    i stopped using the injection july 2016. i gained weight always tired and sleep less with still no period and sore breast. is this normal and how long till i get my period back

  31. Tina says:

    VERY bad drug! SHOULD NOT be on the market. I was ill informed by my gyno. Only told to be careful b/c I could experience minor weight gain. I’ve only had 1 shot. it’s been 1 1/2 mos and I’ve already gained almost 20 lbs. I feel VERY emotionally unstable. I have suffer daily with: headaches, joint pain, visual disturbance, EXTREME lethargy, irrational thinking patterns, unquenchable hunger. This is an absolute nightmare and daily I feel like I’m losing my mind. PLEASE DO NOT TAKE THIS DRUG! It clearly is not good for the human body!

    • Mallory says:

      Hi I’ve read so many reviews and here it’s all negative I’ve tried so many different bc pills and the Nuevo ring all to make me extremely emotional and irrational and some make me bleed for weeks on end. My dr this week said this is my best option for my moods as far as I’ve read I am now terrified!!! Is the weight gain and moods really that terrible right at the start???

      • Katie Simmons says:

        i just took my second depo shot and my moods are absolutely terrible already. the first three months were a piece of cake but now i can barely make it through the day. i question my relationships and overthink things regularly and i am very emotional. i hope this will end soon. i am not getting the shot again so hopefully since i have only gotten two shots then my side effects after won’t be too bad. hope this helps

  32. Amber Ritchie says:

    I am 28 years old. My husband and i are trying to conceive. I was 5 weeks pregnant with symptoms bad, i went to my dr for a blood test. At 4 weeks it was negative. I recently as of yesterday went to the er to get some answers! I was sick as ever! After several test. I was told my test came back negative and i had already gotten a faint positive on a urine test. A few weeks before. So anyway. The dr told me i had a miscarriage. And i also had a cyst that ruptured and bled out on my left ovary! Ever since i started taking the depo shot i have had reoccurring ovarian cyst. That put me in my bed for a week. It ruptures im sick for a whole day. And then my period hits! Im not taking the depo anymore and haven’t been for about 3 years. Im not infertile but since being off the shot i haven’t been able to conceive. Until now. But my one time of conception. I misscarried! Im still upset. At myself for listening to everyone who said yeah you should get the shot!. I have 2 other children. I missed my shot for 3 months in between my son 11 and my daughter7. I have faith in God. And i know every thing happens for a reason. I just pray he blesses us with another child. To raise in his honor! Is there anything i can do about this?. These cyst cause severe damage to my body. I lost my child bc my system had been poisoned by a ruptured ovarian cyst.

  33. Brittney says:

    I have been on the Depo Shot for about 6 years now, and I loved the idea of not menstruating, but for the last year or so I find that I’m always tired even when I get enough sleep, my body aches waking up in the morning and I can not lose weight to save my life and I am eating well and exercising 4-5 days a week. I have no motivation to want to go hiking or outside anymore and I couldn’t understand why until doing further research. Now after hearing all of this I am nervous to get off the shot but I also want to be able to have another child without complications…..anyone else with similar side effects and how did you cope coming off the shot and doing a different form of birth control?

  34. Amenia Nelson says:

    My daughter has had two larspcopic surgeries for blood clots and lost a tube. She gained a tone of weight overnight. Her mood changed she started to act like a old woman.

  35. Jennifer Tarren says:

    Began shot may 1. 1.5 yrs later, decided to quit. Erratic heavy bleeding and regular nausea and mood swings were not worth it. Next shot scheduled for nov 1. Didn’t get it. Glad I didn’t want kids right away. Beginning of January commenced the 15 months of eternal bleeding (and still counting. Probably had a total of 30-40 days out of 420 not bleeding or spotting. It’s my new normal now, but am not keen on any other hormonal contraceptives. Don’t depo before you know.

  36. Edith says:

    Prior to me getting the Depo Shot and that was back in 2002/2003. I made sure I read all the side effects which were nothing like all the other birth controls. I was on the Shot for 5yrs and gains 15lbs within one yr. I got off the shot for a few yrs then back on to discover later on my hair was thinning out. That side effect was NOT on the box nothing mentioned about your hair thinning out or falling out. In addition, after completely getting off the shot, I got pregnant & had a miscarriage for no apparent reason. It has been 8yrs and the worst part of the adverse side effects is I am constantly feeling pain in my buttocks muscles where I had been given the shot. Unlike others, my shots were on my buttocks and it is a very discomforting feeling especially when I’m wearing a belt. It becomes very painful and an extremely uncomfortable feeling. I don’t know what to do. It scares me.!!!

    • Heather says:

      Thinning hair is often related to a thyroid imbalance. The reason thinning hair was not on the box was because it’s unlikely the Depo shot caused that symptom.
      Also miscarriages are awful and I’m very sorry for your loss but up to 50% of pregnancies end in miscarriage. It’s highly unlikely that the miscarriage was related to the Depo shot.

  37. Kayla says:

    My doctors never warned me about the side effects. They told me that they are just like any other birth control symptoms! After I got off the first brith control the “Nuva ring” I was pregnant with our first a week later. So I thought yeah if it’s like that I should be fine. It’s been 10 months sence I’ve stoped the depo shot and I have not had a period sence I first got pregnant with our son. He’s 2 now. I’m scared that because of the shot I may not be able to have more children. We didn’t want them to be too far apart in age but it may just be that way. I blame the doctors for not being more informed and just telling me that “it’s like any other birth control” when yes in ways it is but no it’s not. It did its job I didn’t get pregnant but now I’m having a difficult time getting pregnant again now that I want to have another. I also blame myself for not doing research. I was concerned more about finding an affordable birth control than being concerned about having more kids.

    • Kelly says:

      I am so sorry for you 🙁 I am in the same situation. Took my 1st shot in 2013 and after the 3rd I decided to stop. It was 3 years without menstruation…Now I am under treatment to see if I will be able to get pregnant again, but the doctor is not sure if it is gonna happen. I feel sad because I was not informed about it, just heard that “Depo will be very good for you”
      Today I think it would be a lot better to get pregnant again when my son was 2 months old.

  38. Heather says:

    I was on it for 3 years and the other than a very slight weight gain I had no issues at all. My periods were limited to a couple of days of spotting once every 3 months, and I became pregnant within 6 months of going off of it.
    For me Depo was an excellent positive experience eliminating the worry about missing a pill, and having no periods and no PMS was freakin awesome.
    Just thought I should balance the negative with some positive. Well it might not work for every woman, some of us would highly recommend it.

    • Kim says:

      Good to hear. I had no moods swings until I was coming off it and my joints were like an old woman. Its hard to tell if its the depo or age slowing the body down lol. I am going back on it tomorrow, as im 46 and cant handle the periods any longer.

  39. Hannah park says:

    This is the worst drug ever for women that i dont undetstand how still provided to women. My GP recommended it for “short term” contraceptive method. I had one shot last year in June, i am still getting side effect currently in may almost a year after. I had to see my gyno to stop the bleeding somehow and he told me this symptoms could last for two years. So if you use depo, you wont get pregnant since you will be bleeding all the time, give you a horrible mood swing so no one would have intercourse with you. I have wasted so much money on tampons, appointmemt with specialist, and not to mention that i had to pay for this injection ruined my life for the past year. Do not recommend this to anyone unless for someone you hate so much want to make her life miserable.

  40. Selena says:

    I am 18 and I got the my first depo shot in January of 2017 I didn’t bleed for two months straight. March came around and I started bleeding and here it is may and I am bleeding and cramping ten times worse. Going through pads practically every hour. Haven’t got any other shot since my first one..

    The deposit shot is the worst thing any girl can do to their body.. I hope they take this off the Market quick before it messes up more women.

  41. Michelle says:

    I used depo-provera from 2008-2013 not to prevent pregnancy per se but to reduce periods (since age 12-13, heavy and as painful as you can imagine)–it worked and I got absolutely none during that time. (Being overseas in the military in a highly physical job, it was the smartest option for me.) It worked for me…once, however after my last ob-gyn appointment this year, I was prescribed it again almost cavalierly. I have no need to be on the drug because I’m currently abstinent and in a sedentary job (both of which I mentioned), however the physician recommended it anyway for PMS and heavy bleeding symptoms as a way of relief. But I feel like if I am not asking for that relief through a drug, why would she push it? Although she prescribed it and seemed to assume I would take it, I still felt uneasy. I trusted myself and found this article. I think that considering that bodies change over time, I can’t guarantee the possible positive effects of this drug will outweigh the potential negatives. So I’m not even going to fill the prescription. Thanks for posting this article!

  42. Amgela says:

    I wish I was older and had a choice to go on depo provera because the doctor and my mother thought it would be the best option at 14 and now my bodies screwed I haven’t had a period in about 2 months and I’ve been trying for a child I’ve been on the depo for 6 years and now I’m always getting my hopes up every few months thinking I’m pregnant but nope just another negative.

  43. Karen. says:

    I started on the depo when I was 19 after suffering years of terrible heavy periods. My period stopped altogether and I was glad to see the back of them. The only side effect I had was a 7lb weight gain. I stayed on the injection for 8 years. I had a bone scan and that was normal. I came off the injection and had no period for a further 2 years, my doctor put me on the pill for a year to get me back into a monthly cycle. Then I came off that. My period was erratic for 6 months and then they returned back to a normal 28 day cycle and now I have 2 sons aged 4 and 3 years old.
    Other women I know have had similar experiences to myself but as with all hormonal contraception it’s trial and error. What is suitable for one person, may not be suitable for another.

  44. Vera says:

    I just got the shot last month my period started on the 7 th day of this month and today is the 20th and I am still spotting, if I new I would bleed this long I would have just kept my heavy flow, I got the shot to decrease my fibroids, I am so upset I’m constantly crying.i hate the depo- shot.

  45. Diana says:

    Depo shot was the worst thing I’ve ever experienced with something I’ve put into my body. I was manic, it was scary and NOT MYSELF. I had to get the reversal shot and I normalized within 30 min. Although everyone’s body is different it definitely did not work for me.

  46. Jaime says:

    I gained 100 lbs in 3 months on the stuff, and I was skinny. Ever since I have trouble losing weight and gain it easily.

  47. Grady cannon says:

    I am 48. I was injected with Depro Provera, one time 24 years ago, in my left bottom cheek. It was terrible. I never got another injection, but right after using it I started with health issues like Fibromyalgia and IBS. I had always been super healthy before taking that horrible shot. Within a few years I had three cracked vertebrae. I have had severe pain in the left side of my neck, left side of my head and left arm, which I attributed to these skeletal issues. Last year (2016) I was diagnosed with Pelvic Congestion (varicose veins in the pelvis, thought to be caused by changing hormone levels, weakening the vein flaps, which are suppose to close and keep blood from flowing back into these veins. When the flaps fail, the blood pools in that area and keeps the adequate amount of blood from circulating to the legs and back up to the hear). My leg muscles started to deteriating, to the point I couldn’t walk, owing to lack of circulation in my legs. I have had a vein embolization and full hysterectomy to try to elevate the symptoms. While I am able to walk now, I do not have adequate circulation and I am limited physically. I have sharp sporadic chest pains now, and I am completely unable to go outside if the temperature is above 78 and the humidity above 60%, because my legs begin to hurt to the point I can not walk within moments of being outside. It is crushing my soul. I still have terrible pain in my neck and shoulders and left side of my head. I now know that pain was not all caused by the skeletal issues, but instead, circulatory issues from the pelvic congestion. Either way, I believe Depro Provera is at the root of all of this, especially after reading so many cases of the horrible side effects on the bones, veins, heart, neurological system, and emotional wellbeing of the women who have taken this terrible drug. We have got to get this poison off the market!!!

  48. Laura simangele the says:

    My name is laura I stopped using depo 5 years ago and now I have been trying to conceive but I can’t I regret it

  49. Nancy Godkin says:

    My 20-year-old daughter was diagnosed with a small pituitary tumor that started with a pituitary hemorrhage after taking the Depo shot for 2 years and then stopping the shot. When she first started Depo, she had a fibroadenoma breast tumor removed at age 16. Then, after discontinuing the shot, she had sudden sever depression, anxiety, headaches, mood swings, fatigue and has not menstruated for 2 1/2 years. It is hard for the whole family. We pray that her pituitary tumor will resolve itself as they sometimes do. On the other hand, it could continue to grow, cause more sever headaches and threaten her vision. We pray that her menstration will return and she will be able to conceive. I believe that there are many other women with pituitary abnormalities due to taking the Depo shot and the drug companies need to own up to it. I also believe that drug company representatives read comments such as this one. I wonder how those people can sleep.

    • MaryEllen Payne says:

      I am so sorry to read this. I have a Pituitary tumor I believe is linked to Depo Provera . I am seeking a lawyer to file a lawsuit.

      • Monica Riojas says:

        Thats good , you know your body well before and after we start up on all this monster medicines and its your rights !!! Im going through tough times too after only 1 depo provera injection and im not the same anyone , i got the shot February 21, 2018 and im still having issues bleeding and all ?!!!

  50. Jessica says:

    I am 15 and a junior in highschool
    I’ve had a boyfriend for 2 years and due to the side effects of depo I hardly trust him, I can’t disagree with anyone or I will flip out, and if anyone wants to take credit for anything that I helped with I will hate them.

  51. i was on the shot since 2015 and stopped march of this year it’s been 4 months and i don’t have a sex drive i don’t know if its due to being dry or what please help me will my sex drive come back if so when

  52. AngryInPhoenix says:

    The Devil created Depo! I was put on that junk back in 2010 to help control heavy periods brought on by fibroids. Awful, awful, awful. Had terrible side effects, both physical and psychological. My BP went through the roof! 180/100. I’m still on BP meds 7 years later because of it. I should’ve sued that damn gyno for putting me on that crap. It ought to be outlawed 🙁

  53. Kim says:

    If you want children in the future, or you have no children DO NOT TAKE THIS INJECTION. It is great to stop periods and helps if you suffer severe pms. When coming off the injection expect bad mood swings and joint stiffness, you will feel like your mind wants to do so much but your body says wait. Wait. Wait.lol. at 46 I’m going to go back on it as my periods have started to get bad. Heavy clots. Odour change. Effecting my self confidence. Working is impossible each cycle making me feel unreliable, and my moods with people are uncontrolled, effecting my relationships with people i love and love me. Hope it works out. Good luck people, what ever you decide.

    • Vivi says:

      I’m 19 soon 20 years old and I’m using depo since one year and a bit, I started using it bc I was a wreck during my period, I was so in pain. I couldn’t go to work everytime so I started using depo. My period stopped and I feel no more pain, yes I gained a little bit weight but I’m skinny so it’s not a problem. I was happy with it but now I feel anxious often, I think I have an awful sickness, I got problems with my heart or I’m just thinking that idk…I’m very moody. Idk what to do now, I heard of the side effects when I stop using depo, I’m afraid of it. And I don’t know what I should use when I stop using it.

  54. Jessica Brisbee says:

    So glad to see women sharing their experiences and raising awareness of the aftermath from taking this drug. I used Depo-Provera for 5 years (age 13-19), but with being so young I never really made the connection between the medication and the ways I was feeling. For the entirety of being on the drug, I was horribly depressed and experienced major mood swings, impossibility of losing weight, terrible acne, and many other side effects. Just as with most accounts being told here though, the worst came with coming off the drug rather than being on it. I got pregnant 11 months after taking my last dose, miscarrying 6 weeks into it due to such severe hormonal imbalance that I have since become convinced was caused by taking Depo-Provera for such an extended period of time. The many side effects were so severe, I ended up having to see an endocrinologist regularly and was later diagnosed with PCOS, directly caused by these hormonal imbalances. It took years for my period to regulate again, though now are always accompanied by painful cramps and tenderness that I’d never had trouble with before. Although I was originally told the side effects and suggestion to not be on the drug for a long period of time, once I began taking it I was never advised to come off or made aware of the possible damage that it could do. Being as young as I was, I feel my ignorance was targeted as a way to maintain my status as a consumer and the consequences ended up being more than just a little sadness here and there – among so many other things, the consequence was my child. That in itself is reason enough to say, I would never EVER suggest this drug as an option for birth control or anything else. Undoubtedly one of the biggest mistakes of my life, and my most regretted decision.

  55. josy says:

    I took one shot of depo on may 2017…I didn’t mestruate for the 11 weeks but suddenly on my last week I started bleeding and its now a month….I don’t know when will it stop I’m tired!!

  56. Samantha says:

    I was on the depo shot for 8-9 years. While on the shot I had a surgery to remove my right ovary due to cysts from depo in 2012. Well while still on repo fighting depression major mood swings lack of sex drive and constantly bleeding in 2016 I became pregnant, once again I was on depo and only had one ovary. I have had no stop problems with my body and my doctors speacilist and obs. I have been bleeding for about two and a half years even while I was pregnant. Thanks to the depo and not knowing this horrible shit that can happen my life has been falling in a downward spiral. I am seeing another speacilist and pretty much all they can tell me is its going to take some time.

  57. Laura Jenkins says:

    I am a recent Depo-Provera victim. The events are as such, last November (2016) I started experiencing irregular menstrual cycles, I would not bleed for a month or two, then bleed for a day, then not for a few weeks, then bleed again for many days. I would also experience severe pain in my abdominal area, to the point of going to the ER, I was diagnosed with ovarian cysts and was sent on my way, after months of this continued chaos, I was seen by a OB-GYN who, after running test, told me that it looks like i might have Endometriosis, and without surgery, there was no way to be sure, so he was going to treat me as though I DO have Endo, and proscribed birth control as a solution to my issues. I am already taking a handful of pills everyday, that I cant always afford to refill. I also am not a fan of IUD’s. The other option I was given was the shot. 1 shot, every 3 months. I figured that since I end up seeing a doctor at least that often for the various other medical issues I have, that sounded like the best option. Within about 2 hours after getting the shot, the severe pain I was in stopped. All that was left was a minor discomfort from the muscle spasms that occur during menstruation. However, it has been 13 days since I took the shot, ant 14 days since I started my menstrual cycle. I also have been experiencing mood swings. I take an anti-depressant on a daily basis for just that thing, now they are getting worse. My doctor is out of the office for the next week, and the call a nurse I spoke to said to go to the ER. Now I’m really worried.

  58. Kim C says:

    I took the shot for about a year after my second child and gained so much weight during . I stopped the shots and have been physically sick for 18 years . Diagnosed with Fybro , depression, and so many surgeries and my body does not fight infection well. My youngest son , now 18 made the comment that he has always known me to be sick or just never feeling well . I have a hard time remember things which effects my work and family

  59. Gabrielle says:

    Although this was published some time ago, I feel it is still relevant. 6 years ago I decided to switch to the shot after speaking with my doctor and trying out several pill-form contraceptives that did not work out. When I was on the shot, I love it. Early on, I lost weight. A LOT of weight, a scary amount of weight to the point where I needed to monthly check in with my Dr. to make sure it was still safe to stay on the shot. Of course as a 21 year old in college loosing seemed to be a blessing so I stuck with it. Looking back I wish I took that to be my warning sign. Flash forward 5 years- a week leading up to my shot, I could feel my body go into withdrawal symptoms- flu like symptoms nausea, shakes etc. When I received the shot, the body aches lasted a couple days, then it was back to normal. After 3 rounds of this I took this to be a sign that I should stop this medication, my body seemed to be getting dependent on it and I was getting married and looking to have babies- maybe not soon but someday. Flash forward a year and a half to present day- my last shot was in January. This means by April the medication should have been up and my body getting back to normal. It has been anything but normal. Mood swings, nausea, extremely sore breasts, and not a trace of a period. It is now September and Ive been married a year. We are talking about babies and because of my constant nausea and other odd symptoms we thought we were pregnant a couple times and were actually really excited! After a few tests, we were let down and Ive realized my body is just crazy. Ive called my Dr. and theres nothing she’s suggested but waiting it out. She said it could take up to a year (next April) for me to being ovulating again. How can this be normal and with no forewarnings? I know it is impossible to become pregnant and I know Im still young but knowing you can’t even if you wanted to makes me want to cry. If there is anyone in the Boston area who can help/give advice/ or no a helpful practitioner I am open to all suggestions. Thank you.

  60. Kaneisha says:

    I was on the depo shot from 2008 to 2015. I decided to get off of the shot because I was no longer sexually active. The only side effect I experienced was weight gain. I am currently back on the depo shot because I am tired of dealing with periods. I absolutely love it and would never use anything else. I have several friends and family members who experienced bad side effects from other forms of birth control and have now switched to the depo shot and have no problems besides a little weight gain. All birth control can and has caused adverse effects for some women. You just have to find what’s right for you and make sure to educate yourself about how it will effect your body and serious side effects associated with it.

  61. Sally says:

    My daughter has suffered from horrific periods since she began her cycle at age 12. After 2 years of unbelievable cramps and gushing blood the gyno put her on BC pills, they did not work. So, tried another and yet a 3rd BC pill. Finally the gyno offered Deposit Provera. I wish I had changed gyno docs before they injected this toxin into my child. She was 17 & 1/2 yrs old at the time. It has been one & a half MONTHS!!! I wish I would’ve found this blog when I was doing research. The gyno was so positive. I believed her. I felt safe for my daughter. I have since called the FDA and I am to make a report. Then they want me to call the State Medical Board to report abuse to patients! WHY??? I watch my daughter suffer everyday worse and worse. She’s a senior and she’s on pain meds always. The gushing blood, the unacceptable pain, the increase in appetite! Where did this devil poison come from? How is it even available to anyone, especially teenagers who are suffering horrid cramps and bleeding? How did the FDA accept this to be on the market? Once the shit goes in, there is no way to stop the destruction, irreversible pain and suffering!!!!! Please help! Regards, A mother suffering in silence. God help us all, my poor baby.

  62. Emma says:

    At 18 I jumped at the chance to have a 3 monthly shot that could stop my periods all together and mean I don’t have to think about contraception until my phone reminded in 3 months time. I was on the depo for just shy of two years and raved about it. Then I stopped to try for a baby with my now husband of 7 years.
    We weren’t informed of any dangers to our plan when I told my gp we were trying for a baby and within weeks of leaving the depo I was pregnant, we were thrilled and at 7 weeks we lost our first baby. A strong bleed and one fun night later we were pregnant again and at 11w 6d we lost our second baby on our honeymoon the night after we married. From there I bled irregularly and frequently until falling pregnant with our son (now 6). After having our son I bled horrendously, erratically and frequently until falling pregnant with our daughter (now 17 months) and now I’m back to bleeding almost continuously. This is destroying my marriage and my mental health.
    Only this week was I informed that the depo has adverse effects on bone density and that with a family history of various forms of arthritis, crumbling spine and osteoporosis (amongst other bone issues) I should never ever have been allowed to have the depo.
    I am currently waiting on blood test results as at the age of 26 I have possible fybromyalgia, rheumatoid arthritis and a possible deterioration in my spine causing a trapped nerve leaving me with serious pain 90% of the time.
    I’m distraught that I made such a terrible decision at such a young age without being fully informed or even comprehending that such a quick and easy decision (being encouraged by my then gp) could negatively impact my entire life to such a horrific extent.
    Only now are there talks of reffering me to a gynaecologist and since researching the depo this week (the truth is well hidden!!!) I hold out very little hope for fixing this mess

  63. Kiana James says:

    I was taking depo- provera from ages 16-20 and then again from ages 21-24. I finally decided I had enough when I noticed some weird body changes. Most I still have to this day and I am now 27. I experience hot flashes, mood swings, which to some people I am now known as a person with an attitude, and bad body aches. I have had some hair loss (some spots are not growing back) and a lot of weight gain. I have been off the shot since the age of 24 and my period just came back last year. I discussed this with my gyno and even he thought it was strange that my period was delayed for so long. I have been trying unsuccessfully to have another baby. If I knew what I know now, I would have never taking this shot. I am currently not on any form of birth control and I plan to keep it that way because of these experience.

  64. Jaime says:

    I lost a bunch of my hair, my libido went from high sex drive down to almost nothing. I’m literally dry Nd this never was a problem for me before. I’ve been depressed because I can’t get off and constAnt anxiety. the depo shit is my biggest regret. destroyed my last relationship and might be drstfouing my current one too. this drug is evil!!! Help!

  65. Christine says:

    I would have to completely disagree with this article. I was on Depo Provera for 6 years to prevent debilitating cramping when I get my period.(just recently diagnosed with Endo) I lost 35lbs while on the shot, this weight I gained before I started the shot, by just eating healthier. I had no side effects from it, and I got 6 years of my life pain free. I have an older sister who was on it for 2 years, no side effects, she went on to have 2 kids, no issues getting pregnant and no problems during her pregnancies. Its unfortunate that a lot of women have a bad experience, but don’t take it away from the women it has helped. This shot gave me my life back.

  66. Jeanette Byrne says:

    I’ve been on the depo injection for 12 years, after having my son and daughter and had no problems… until recently when my partner and I decided to try for a baby and I chose to stop the injection. Wow! I was never ever told about what I was about to experience, and always just trusted what I had been taking was ok!! Nieave really!
    I’ve been off the injection for 19 weeks now and have had the most horrendous time. I’ve been tearful, angry and sobbing most days (which is ridiculous as I have a great life) my poor husband and children have been living with a nut case! My breast are ridiculously sore, even just on my bra, and wake me in the night if I move. I litrally can’t stop eating, which isn’t like me at all, and to top it all off, I’ve had morning sickness everyday, actually throwing up, every single day. Just the smell of someone’s perfume makes me sick. Finally I’ve been exhausted!!! I’m a mum to a 14 and 12 year old, have 2 dogs and work full time as a physio at the hospital, whilst training at the gym every morning, and recently I’ve been exhausted to tears most days.
    I wouldn’t wish this on my worst enemy! I’m appalled at a health service, that I myself work for! I spent years doing medical research to treat patients and I’m disgusted that this drug is alloud to be administered without patients knowing the consequences.
    I would welcome and support anything that assist in letting women know what they are letting themselves into when taking this drug. I hope more is done to prevent how myself and other woman feel.
    I haven’t had a period and I’m so worried this has made me infertile. I just pray that’s not the case.

  67. Ellen G Paiva says:

    I was administered the depo provera shot about 10 years ago and ended about 4 years ago. I was told it was no longer available on the market. I believe that it is the cause of my osteoarthritis in my knee joints and now my hip joints, which came on suddenly and rapidly. I am looking to see if there is a class action lawsuit against the manufacturer as there is in Canada.

  68. TARA CORETHERS says:

    In 2001 I was 130 lbs. and tried the Depo. I started gaining weight and bled everyday for six months straight. And went up to 200 lbs. This is 2017 and I am still trying to get the weight down. I would rather have a 1000 babies than do it again. My weight is now 154 lbs.

  69. Veronica says:

    I had one ONE Depo Shot! It was the end of my great sex life as I knew it. Within a week I started bleeding. I thought it changed my date to have a period. By the third week I knew I was in trouble when huge blood clots drenched my slacks & I almost passed out. I was rushed to the ER and was told I was hemorrhaging. My OBGYN then informed me I’d have to have an emergency hysterectomy!! I had only taken the shot because my medical provider said I wouldn’t have to bother with having periods interrupt my life. WRONG! I would never recommend this horrible shot! I wanted to have one more baby now I can’t. It changed my sex Life forever. It will never be the same.

  70. Amalia says:

    I was given the depo shot 3-4 years ago. Before having the shot I was a normal 23-24 year old, everything seemed fine until 2 months into the depo shot.

    I went from being a little wacky (montly due to period) to a complete and utter mess. I would cry myself to sleep every single night and I had no idea why I was crying for months. I was extremely depressed, emotional, crazy, angry and everything else in between. After two months and having felt that way I decided to NOT take the depo shot ever again. I thought everything would go back to normal but no, it only got worse from there.

    First month into depo, period was on time and was ok nothing crazy, month two along with crazy feelings my period lasted a lot longer from 3/4 days to 6/7 days with spotting in between the weeks. Month 3 came and I basically had a period for 3 weeks in a row with spotting on the 4th week, for 8 months. 8 MONTHS!!! I went to the hospital to figure out what the hell was wrong with me. The doctor said that my uterine wall was very thin which was why I was bleeding for so long?? Not to mention my libido went down the drain by month 3 and continued to fizzle in the years to months to come. I didnt want to be looked at, touched, nothing, because I felt useless and I had no drive and couldn’t/can’t get myself to physically want to. Emotionally and mentally I do, but physically I couldn’t/ can’t.

    Its been almost 4 years since and I have horrible periods, crazy mood swings that not even satan himself wants to look at me, horrible cramps and clots that I never had before (Ive had my period since the age of 11). Zero sex drive, gone, poof hasnt made its way back at all since then either. When I do have sex extremely painful and uncomfortable, sharp shooting pains and dryness.


  71. Serena says:

    I’ve been on Depo for almost a year (started at 19 yrs old). I get mine at a clinic for woman (County family health place). I tried the pill, but that made me sick and hormonally I didnt feel myself. So, they put me on depo. Everytime I experience a new symptom (that’s not in the brochure) I’d Google it to see if I’m not the only one suffering. Then when I’d go in for another shot and tell the nurse, she tells me to stay off of the Internet and not believe everything I read. I’ve had headaches, cravings, I don’t have a period anymore, but I have ALOT of discharge (I have to wear a liner everyday and change it 2X or 3X), I’m tired and have an anger issue to the point where I get mad over the smallest thing. For the past 2 days I’ve been vomiting and I can’t stand to eat or look at food and my next shot is towards the end of next month.

  72. Billie J Reopelle says:

    Before telling my story which didn’t have a happy ending I want to state a few things.
    1st any hormones will severely mess with your body
    2nd all drugs carry side effect
    3rd THIS ONE IS FOR THE TEENS you can’t put ALL your emotional and physical issue on any BC, you are a teenager going through hormone changes you’re not going to be the same way you were 2-6 yrs ago.
    4th it’s a 3m shot of course it’s going to take longer to clear out of your system
    With that said, I was on it from 12-24 I had an amazing 11yr run THEN that last year I started bleeding almost everyday. However I’m a strong woman and YOU Can Be too! I do recommend STOPPING it if you are on it. Push yourself to move forward…YOU choose what happens now. I’M not saying life’s a cake walk I have ADHD, depression, seizure disorder. I was molested as a child, rape, my mom in a wheelchair my who life, from 9-17yrs old I was in Mt state custody, 18-26 married-widow. Yep, I’m a SURVIVOR!, a MOM!, an I’m LIVING cause I deserve to!, YOU CAN TOO ? LADIES YOU

  73. Rene’ Downs says:

    I was on Depo Provera for 5 years. Two months ago I was diagnosed with Deep Vein Thrombosis (DVT) and have blood clots in my left leg. According to the hospital, this was all caused by the Depo injection. I was told to get off of it, which I did. Now I’m on a blood thinner for at least 3 months and have to have ultrasounds every month until they’ve dissolved.

    • Sarah says:

      Hi, I can sympathise with you as I too ended up with DVT in my leg from this injection. Was told no more contraception or anything to help through menopause. The following 3 months were horrendous. I actually wrote my experience on Coming off Depo-Provera can be a woman’s worst nightmare board 2yrs ago. All the best.x

  74. Latika Salian says:

    Depo definetly did not work for me. I took the shot in August and i am still bleeding, some days are worse.

    I would not recommend this to anyone.

  75. Leslie Caines says:

    I was on this at 13 for a hormonal imbalance, I was perfectly fine. When I stopped it my periods came back after a while. Now I’m 18 and I got my second shot 10 days ago and the cramps have been absolutely unbearable. After my first dose I had heavy bleeding and cramps so bad I had to quit my job. The gynecologist I saw told me it was probably just the first shot and getting the second should even it out but here I am doubled over in pain and bleeding again. Definitely not getting this shot ever again.

  76. Jennifer says:

    I was on it for 5 yrs in my 30’s. I had some breast tenderness and stronger odour while on it but it took care of all the period problems. When I came off it my periods started up the next month. I am contemplating going back on it again to control the debilitating migraines I get from hormones the week before my period. The gyno said to use it but reading all these comments give me pause. I am now 51 with no menopause in sight and the pain meds are getting to be too much. Seriously debating this .

  77. AC says:

    I’ve been on the depo shot for a few years and had a great experience with it until this year. I enjoyed not having periods and being able to spontaneously enjoy sex with my husband without worrying about pregnancy, which we plan for but haven’t been ready for yet. This year I dealt with painful ovarian cysts, which seemed swept under the rug by medical professionals as not something to worry about. The worst pain I’ve ever felt in my life is not “nothing to worry about”! I suspect the long-term use of the depo shot is to blame somehow, even though this concern was also ignored by medical professionals I spoke to.

    Although I had a great experience with the depo shot at first, I worry at the lack of long-term studies. I agree I was never given enough information. Luckily I know how to vet online sources for myself, or I’d be much more in the dark! Some people are bound to have bad experiences with any drug and I can’t say depo is all bad since it’s just now I’ve had issues and some say you shouldn’t use it longer than about five years anyhow. It’s not right that I received so little information from professionals, and much of it was conflicting. Sometimes I was told of the risk of bone loss, and other times that was completely downplayed, for example.

    I’ve decided I’m done with the depo shot. The horrible withdrawal symptoms many women have described going off of the shot remind me of the withdrawal symptoms of psychiatric medications stopped suddenly. These medications are advised to never be stopped “cold turkey” but to instead have the dosage lowered a little at a time so you “taper off” of it. Why is a similar option not offered or even discussed for stopping hormonal birth control? It seems like it would save women a ton of emotional pain! I worry about going off of the shot myself and want an option to “taper off”, but since this isn’t an option I’ve ever heard of being offered, is there any way I can try to do this? Can I request a gradually lowered dose, of the shot itself or some other way of taking gradually lower dosages of progestin?

  78. Anonymous says:

    This was my first time taking birth control, depo has messed up my monthly cycle. I’ve been bleeding for 6 months straight, heavy periods, having to change my pad every hour. I became fatigue, headaches more often, shaky, not able to go outside or go to work, & ive become more tired everyday. I’ve became anemic because of depo. The pain is very unbearable & it’s the first and last birth control I’ll take. I’m not sure when my body will come back to normal, any advice ? I even talked to my obgyn and they said it’s different for everyone..

    • Jessica says:

      I’m sorry to hear that you had such a bad reaction. While I was on Sept everything wasd fine. If you reasd my post below you’ll see I suffered and I’m still suffering from the affects the depot had on my body. I hope that your recovery is much faster than mine has been.

  79. Crystal Lowe says:

    My husband and i had a mid life crisis. We have been separated for 2 years. He filed for divorce in March 2016. I recently learned he has a mistress, he left home and it has been so terrible because i could not endure the heart break, then i came across Dr Mack on the internet about his good work and how he has brought unity among couples who had relationship issues. i decided to contact Dr Mack through his Email:dr_mack@ yahoo. com and luckily he was able to bring my Ex-Husband back, Dr Mack is real and genuine and he has the powerful to restore relationship.

  80. Laura says:

    I’ve been using depo for three years. I don’t have too many bad side effects, but on and off cramping (no bleeding) is worrying. So far, no doctors or nursee have been able to give me answers for this. It’s driving me crazy!

    Also, there was a time when I lost my health insurance so I had to miss the shot. It was horrible! Constant spotting and period cramps.

    I would stop taking it but I’m worried about withdrawal. Plus, I’m worried about having my heavy periods return, which is why I got on depo in the first place.

  81. Jackie says:

    I was given depo provera in 1988. I had just had my second daughter 14 months after the 1st. I was told by my health visitor (UK)that if I didn’t want another baby for a while I could have this fantastic new injection that didn’t have to be remembered to be taken with no side effects etc. The Dr actually came to my house to give me the injection she gave it me then told me to sign consent then left saying she’d be back in 10weeks.i started bleeding that day and didn’t stop. I was 19 at the time and had loads of energy and no depression. Within weeks I was permanently tired and really depressed. I didn’t know at the time it was depression I just thought I felt ‘bad’.my relationship ended because I didn’t want sex and I kept getting in a temper. I also piled on weight and felt like I had never ending pms. The Dr came back in 10 weeks gave me another injection and said that it would cure all the symptoms. It didn’t. They got worse. I didn’t have another injection. It took about 6months for my symptoms to go and to shake off the pms. I felt fine after. I’d never advise any woman to have it it was awful.

  82. Jessica says:

    I was on Depo for about 7 years. In 2012 due to not being able to afford the injection anymore I stopped getting the injection.
    The first 3 months were a nightmare for me. I was one of those lucky people who never really got cramps. For 3 months straight I had cramps so bad that I could not get out of bed.
    Then around month 4 I started to bleed. I thought thank God the worst part is over. I was wrong my period continued non stop for 4 more months. I went to my doctor several times during this time and was told give it time it will work itself out.
    It’s now almost the year 2018 and my body still hasn’t adjusted. How long am I supposed to wait? Some months I have a periodf for 7 days normal healthy no problem other months I start and it doesn’t stop f or 60 days. Then there will be times that I’ll go 3 or 4 months without a period.
    I regret ever going on this birth control f or the pure fact that I feel like I have no control over my body. And my sex drive has suffered because I don’t wasn’t to have sex whiole on my period because it’s so messy. I wish moire information had been avaiable about what could happen if I ever stopped this meddication.

  83. Jennifer says:

    I myself have never taken this shot, but 2 of my sister and a cousin did. It caused weight gain, mood swings, thoughts of suicide and excessive bleeding. I told my 14 year old daughter and her father these things when we were discussing birth control over the phone. So instead of listening he glee his girlfriend take our daughter to the health department and they let her get this shot. I am furious.

  84. Omega Wilson says:

    I myself has been taking the Depo shot for over 8 months and has had continuous bleeding. I was told that after 6 months the bleeding would stop, but has not. This is ridiculous!!! I had recently taking the shot after my son was born 13 years ago and did not have this problem. Not sure if they are using different stain of this drug or not. This is terrible and I feel awful. I have lost weight instead of gained. Mood swings, I have them. Now I have to go through the torture of allowing this shot to wear off in my system. This even ruined my relationship with my significant other.

  85. Sarah says:

    The most horrible thing ever! Only had one shot and have felt all over the place. Doctor minimized side effects. I had been diagnosed in 2014 with hypothyroidism which was under control but now hormone levels are off and feel happy, sad, angry, hurt, etc. all the time. It was three months ago when I had the shot and was told it takes around 6 months to get back to normal… can’t take much more.

  86. Melissa says:

    I only did two shots of depo and i was like no more! I was literally working out six days a week and was gaining weight and couldn’t figure out why and then i remembered i was on the shot..i then went and looked up the side effects and what reviews said about it and i was telling myself i won’t get another shot..before the shot i was steady loosing weight and then i gained the weight back being on it plus more..but reading that women in the shot for 2 years or more couldn’t loose the weight at all that being on depo they couldn’t loose the weight from being on the shot that really scared me and i choose not to get another one! scary! wish i wouldn’t of listened to my doctor and her telling me it’ll help but it hurt me more than actually helped! it was already a hard work loosing the 15 pounds i lost but gaining it back from a shot my doctor recommended plus more i was beyond frustrated.

  87. goombah says:

    I like Depo Provera because I don’t have periods and I don’t have to worry about getting pregnant again. I didn’t have any issues with it.

  88. tumbah says:

    Depo Provera is awesome! You can use it to get rid of your periods altogether! I used it for a decade and then had two kids. Now I plan to get on it again.

  89. Stephanie Teeters says:

    I think I got Cervisitis from it. Had a horrible infection in my cervix. Got told from a friend it could have been from this shot. Beginning to wonder if it’s true. Any ideas?

  90. Esther says:

    I’ve only had the depo shot once and I had a horrible experience. First everything was fine then a week into the shot I started having really bad mood swings, I started feeling depressed for awhile I couldn’t do nothing I felt horrible then one day it was gone and
    I could say a few days later i started getting really bad cramps, I could sleep, eat, move or lift anything. One day I felt a little better and I wanted to go out shopping so right when I was about to leave my apartment I felt a rush of something like if i was getting my period I went into the bathroom and checked myself and in my panties there was big white sticky clumps of tissue with brown blood I was scared so I went to the hospital and they told me it was totally fine and I believed them because after that all of my the pain went away. A few days after that i was feeling great I had no cramps no mood swings I was going back to normal until I couldn’t eat anything every time I ate I would throw it up I couldn’t eat nothing I lost about 6 pounds then the really bad cramps came back and i started getting a really bad rash, I couldn’t stop scratching I started getting hurt cause it was so itchy I couldn’t stop. I felt like this was never going to end, and it was time to get the shot again and I was like no way. My doctor had told me if I get off the shot it should take 3 to 6 weeks to get my period back and now it’s been 8 months and I haven’t gotten my period and I still get rashes cramps and mood swings but I don’t get them that often but I would never recommend this shot to anyone

  91. I only have tooken the shot about 5 or six times and I’m very upset that I haven’t seen my period Im trying to have another child and it scares me to feel like I will neva have kids again this isn’t fair and wasn’t explained to me when I was being given the shot will I ever have kids agsin?????

  92. I only have tooken the shot about 5 or six times and I’m very upset that I haven’t seen my period Im trying to have another child and it scares me to feel like I will neva have kids again this isn’t fair and wasn’t explained to me when I was being given the shot will I ever have kids again ????

    • lucy says:

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    • Lauren says:

      Don’t get scared, it depends on your body. If you want to get pregnant, get off the shot, no birth control. Allow your body to completely detox. It is recommended that you should try to get pregnant 6-8 months after the missed shot. I got pregnant and everything is fine. Have hope

  93. Rb says:

    Do NOT take this injection!! It is AWFUL. I have experienced the worst time of my life and I have only have one shot. I got it in September and it is now January and I have felt possibly nearly every bad side effect including depression, anxiety, panic attacks, feeling like u are going insane, headaches, body aches, chest pain, leg numbness, vision problems, loss of interest in everything!!, loss of relationships, loss of friendships, trouble swallowing, shortness of breath, neck stiffness, no energy, over tired, barely no appetite, weight loss I have even had to leave my job because of how bad it has got! Feeling lost! Like a living nightmare and can’t wait for it to Be out of my system So that I can feel normal again! This needs to be banned so no one else has to go through this !!

  94. Mary Lou says:

    I have been off the Depo for about 6 months
    I was taking it on and off for about 6 years
    My breasts are swollen and they hurt like nothing I have ever felt! I have cramps but no period!
    I have felt depressed and down since I stopped the shot.
    I am 21 soon to be married and wanting to start a family
    All the symptoms I have encountered made me believe time and time again that I was pregnant
    And each time I would take a home test I would be crushed
    I feel that something is seriously wrong with me all the time
    I do not have the funds at this time to go to the hospital to get things checked
    But I know that is something that needs to be done
    I will never recommend the Depo to anyone
    It is a nightmare and I wouldn’t wish this pain and unknowingness on my worst enemy!

  95. Bethany says:

    I’ve been on depo since May 2015. Since then, I’ve had increasingly irregular and painful periods, mood swings, stomach aches, headaches, and sore/tender breasts even when I’m not having or about to have my period. I got my last shot in December. I refuse to get another one. My husband noticed in two years I’ve gotten more depressed, moody, irritable, and sick in general.

  96. Amber mulling says:

    I took the depo for about two years. Starting at 18 and ending May 4 2017( my 20 birthday). I did not go back may 4 to get the shot and it’s January 2018 and I have tried everything to try to convince. I’m married now and I’m in tears every month because I never knew what this could do to me. I’m so crushed about how infertile I’ve been. I’m so so crushed. I wish this was never an option for me as a birth control. It has ruined my dreams of becoming a mother.

  97. Julie Poremba says:

    I have not really had any bad symptoms except weight gain. I am stopping the injections because of what it does to calcium in the body…I hope I can find a safe alternative!

  98. In my own opinion i would also recommend the use of condoms although am not a great fun of them. secondly all All birth control aren’t the same and since most women have a busy schedule to keep up with they tend to forget to take their medication on time. A great site to find out about the pros and cons of all birth controls options available.

  99. Ebony says:

    I was on depo shot from the age of 17 until my late 20’s, in that time I was diagnosed as bi polar and spent years on various mood stabilisers and anti depressants. I also lost my sex drive. It wasn’t until I started researching discussions between other women who were also on depo that I worked out there may be a link with depo and my erratic moods. I came off depo and all anti depressants etc and haven’t had the erratic moods or behaviour since (normal hormonal changes excepted!) The only side effects I was ever warned about were slight weight gain and possible loss of periods. My sex drive still hasn’t returned more than 5 years on and this has a detrimental effect on my marriage. I feel as though I lost at least 10 years of my life because of the depo injection and very let down by all medical professionals involved.

  100. Kay says:

    Ive began using depo last year I took three shots every three months i stopped after my third shot because I read somehing on facebook about depo stating the side effects and that it wasnt approved by the FDA which made me consider not taking it afterwards.. my menstruation cycle is ok i didnt gain weight as people say but i have been experiencing the restriction part it sucks it ruins the fun in the sheets i been off depo for 3 months .so i missed two shots so far idk I wish i never considered taking that shit

  101. Ashley says:

    I never do this, but I feel it is necessary to share my experience with other women, so they know what they’re getting into. I was on the depo shot for a little over two years. I started taking the depo shot because the doctors discovered I have a blood defect that makes me more susceptible to blood clots and cannot take estrogen. For the most part, the depo shot did it’s job. I did not get pregnant while I was on it, and my period was non existent the entire time. I would spot once in a blue moon, but it was rare and a very minuscule amount of blood. However, my hip joints would get almost unbearably sore especially close to the time when I would need to get an injection. The weight gain was horrible. I would gain about 5 pounds with each shot. It was extra hard because before I started taking the shot, I worked my butt off to loose 20lbs. The smallest I’ve ever been in my life. I was so proud of that.

    The real reason I’m sharing my story is for a side effect that affected everything about me. The depo shot made me into a zombie. I had all my mental faculties, but couldn’t get excited about anything. It was like I was in a haze and not actually experiencing my life. I am a writer and I felt no desire to write or be creative. The scary part was, I didn’t notice something was wrong until one time I was late on my shot and I felt different. I felt lighter and happy. I realized that I hadn’t actually felt happiness or joy in a long time. That’s when I knew what the shot was doing to me. I talked to my Gynecologist and after lots and lots and LOTS of talking and research, I decided to go on skyla. It is an IUD with a lower dose of hormones. It is also local, so I would have less of a chance to have the same side effect as the depo or the rod since both of them go through the blood stream. I was terrified to get and IUD because I heard of so many horror stories. But I talked with my gynecologist for a very long time and we both decided that this would be the best option. If I didn’t like it, I could just take it out. It’s been 6 months since I’ve stopped the shot and I am no longer a zombie. I feel like I’m alive again. Best of all, the woman my husband fell in love with and had missed so much is back again.

    I wish I had known what the depo was doing to me. There was so much of my life I didn’t even know I was missing. The worst part was I was on the depo for my wedding. It breaks my heart that I didn’t get the full experience of my wedding because I didn’t realize it sooner.

    I know every woman’s body is different. I just had to write my experience because this is a side effect that people don’t talk about. It wasn’t a depression. It was a sedation. Please do your research. Try different birth controls to see which is the best fit. Do not settle on a birth control because it is convenient or because you’re scared to try something else. Talk to your Gynecologist. Ask every single question you can think of.

    I hope this review will help. Good luck to you all.

  102. Sandy says:

    I was given the shot to help with my heavy irregular periods, they (doctors) told me that it would put my body in a menopause like state, which sounded wonderful. But, my issue wasn’t after I stopped taking it (which I only did once) but happened shortly after having the shot. I was bleeding so heavily and passing such huge clots, that I had to be rushed to the ER twice for loss of blood. The clots were so huge that I screamed when I passed them. I will NEVER take the shot again. I didn’t have issues coming off of it, because my periods were a nightmare to already. Now I’m begging for a hysterectomy or to be blessed with early menopause.

  103. ROSIE CLONIA says:

    was having serious relationship problems with my husband and it had resulted in him moving out to his friend’s apartment. Everything got worse because he started going to bars and strip clubs frequently with his friend, getting drunk and passing out. He always threatens me on phone whenever I call him because of all the bad advises that his friend has given him. I really love him and we had been dating for 8 years which gave us a beautiful daughter. I had also lost a lot of money on therapists until I was introduced to Dr.Baz by a friend whom he helped to marry her childhood boyfriend; this gave me total confidence and strength to get him back. I did all he asked and after 48 hours my boyfriend called me and rushed back home, things just changed between us emotionally. He has a job and stopped drinking and keeping irrelevant friends. It’s a miracle I never believed was possible because I had lost all hope until I found Dr.Baz. So that’s why I promised to share my testimony all over the universe. All thanks goes to Dr.Baz for the excessive work that he has done for me. Below is the email address in situation you are undergoing a heart break, and I assure you that as he has done mine for me, he will definitely help you too. Contact today : supremespells @ outloom .com

  104. Kaylee b says:

    I do blame my doctor. I’m 17 and told her about exactly what I wanted, she recommended depo. I had to stop birth control pills because of abnormal discharge, random bleeding, and extremely sore breasts. Depo has made me bleed for 7 weeks straight now, and my moods are all over the place. I wouldn’t recommend it to anyone

  105. Jennifer mahr says:

    I was on depo for a year in1998. It was the worst thing i ever did. I was a healthy laid back person. After less then 6 months i had no sex drive was severely depressed experienced blind with rage that scared the hell out of me. I went from a size12 to a 22. Debilitating migraines. Even after speaking to my obgyn they chalked it up to baby blues since i started taking it after the birth of my child. It nearly broke up my marriage it was so bad. It took me more then a year to recover after stopping it.

  106. Jennifer garcia says:

    I don’t know if anyone else had bone depletion problems but I most def do now. I’m in constant pain in my neck(I HAD the neck of a 90 yr old lady per the spine specialist at 30yrs old) I was diagnosed about 10yrs ago after I had a minor car accident and got whip lash. He looked st my films and said you were on depo for long periods of time right? I said yes, like almost 10 yr consistently. He said the FDA and DEA don’t recommend woman on that for long periods of time at all now. It will deplete your bone marrow. Well it’s a lil too late for that now. Why am I just hearing this? I practically live at my drs office now. I get put thru the ringer just to get my pain medication for my neck like I’m a drug seeker/addict:( completely sad cuz I didn’t do this to myself? The 2 disc bulges I had originally had are now benign tumors in there? Idk what’s going on, I don’t think they do either honestly! They don’t know what to do with me. I’m really scared about the outcome of this. What I want to know is my neck going to continue to get worse, I mean it already has by the month sometimes. I can’t go swim with my kids, go bowling, do push ups when I work out and I’m real careful with sit ups. This is affecting my quality of life and sleep. I’m miserable.

  107. Betty says:

    To the woman who says we are responsible to get the facts,We get them from the Doctor! If he knows he should say. Why do we pay them, just for pills and depo that kills people with side effects? Most Doctors don’t even listen, or believe you can feel your own body.

  108. Lauren Benton-Reece says:

    I was on Depo for a year and a half, honestly I had a good experience with the shot. My periods did not happen while I was on the shot, I did gain weight like they said I would, I did experience period symptoms when I was “syncing” with someone. Do it think that more research needs to be done on this, yes. Not every woman is built the same so your body will react differently. Some people have bad experiences with the implant, the IUD, and the pill. You’re going to get bad and good. And I’m pregnant now, a healthy pregnancy, 28 weeks and my last shot was July 2016, I detoxed from birth control, I even used Plan B at some point but we conceived in August 2017. Yes while detoxing I experienced breast tenderness, my period was a little all over the place when it was regulating. Even had one period where I was late for 8 days and then it lasted for 3 days (no I was not pregnant then). I hope that this comment can help. I think Depo needs to be studied more by specific cases so that way we can learn how different women can be affected by the shot. Also, it is not healthy to be on the shot more than 3 years. Don’t do that.

  109. Sandra mcghie says:

    I’ve been on the depo for over 20 yrs. I’ve never been pregnant or had to make that decision. But now at 40 will this injection make changes to my menopause or am I capable of menopause?

    • rhonda says:

      Yes it will be harder because,the side effects lingers.this shot is harder on you as you get older trust me .

  110. Sherry says:

    My 24 yr old daughter went to the dr. For her HPV vaccine and was accidentally given Depo Provera by the nurse. I’m concerned about the side effects

  111. Tracy says:

    I am on the depo and they won’t let me stop taking it and I’ve had bleeding for about 3 weeks and it is really bothering me. I’m going to the gyno next week and I hope things get better. I hate this.

  112. Diana says:

    I thank you for having a site that is educating about the drug. I am in a dreadful nightmare as well. My team of providers never figured out what was going on with me, I had severe panic attacks, heart palpitations, nervous, emotional all the time, extreme fatigue, and body aches, dizziness, just not myself at all! I wish I had known this could happen, I never did my own research because I did not want to become a hypochondriac (but I should have looking back) I felt great with the first shot as it stopped my heavy heavy periods, and by the second shot I started the gradual small things, like loosing my hair, tired, not interested in sex, and just fatigued all the time, but I just figured I have a full time job, mother of 3, that is life. . . by the 3rd shot I was eager to get again, because my period came back after the second shot and the doctor told me to stick with it, normal to have in between bleeding, so I go the 3rd shot and that is when all HELL broke loose. I found myself in the ER for anxiety and panic, and they just put me in the “anxiety bucket” not even putting the pieces together seeing if there was a link. I found out about a week later (after 3frd shot) after my husband and I sat down and really started pin pointed a time when I started all my symptoms and I was completely honest about all my symptoms, as the first one for my husband to recognize is NO SEX DRIVE at all. . . he then looked up Depo-shot and saw that all my symptoms were a match to the bad side effects. I contacted my doctor right away so they all knew (medical doctor and OB) and documented properly in my chart. Now I am starting to feel some fog clear, I had to see a therapist too, to help me with the anxiety that amplified for me. . . NOW, I am patiently awaiting for this Depo drug to wean out of me as providers state that is the only thing I could really do. I am also having other tests ran because is has given me such constant worry and heart palpitations, that I started wondering if I have heart issues, so I am in the midst of that now, but praying for my health, and anyone effected by this drug that has put “the real me” on hold, and I pray to get me back!

    • Diana please give me an update on how things went coming off of Depo . I to just came home from the hospital from spiked anxiety and heart palpitations. I know I need to stop the shot but I am scared of it making me worse.

  113. Angela says:

    I was on the depo shot like 10- 11 years since my son was born but my doctor said it was not good dor my bones and i stopped and got on the merina iud i never had my period on either one or in between either although one thong i did notice is weight gain when i got off depo. Like 30lbs within 1 and a half years i never weighed that much before in my intire life i was 31 years old and 180lbs. Horrible. I never had any other problem i can think of i was not a heavy alcohol drinker so i was in depression but no different than while i was on the depo shot til i started gaining weight Any way. I got off iud cause i got married and it actualy hurt my husband while we had sex i wanted one more child my older one was 11 nd i got pregnant and got my tubes tied i lost weight from breast feeding than after that i got on phentermine and got back to my ideal weight but within a year and a half i gained it all back so im not sure why i didnt change my activity or my eating habbits. I had a tubal ligation after my son and that was first time after 12 years i had my period i had horrible pain first few days every month and bad PMS. So i got back on depo for PMS so far so good first time back on so im hoping to have same effects as when i was younger. I think alot of women blame natural behavior they experienced on the depo being so young and never being that age ypu automaticaly have mood swings and alot of the so called side effects are normal behavior of young female bodys. Thats what i think..

  114. Dawn Fitton-James says:

    My 16 year old granddaughter has just had her second injection and has had continual bleeding, stomach cramps and told by doctor it is just her body getting used to it , now she is having panic attacks! Has anyone else had these symptoms and any advice in coping till it has worked through her system? I am definitely encouraging her not to continue with them!

  115. Bonnie says:

    This drug was recommended to me by my OB as a way to “regulate” my extremely heavy and painful periods. Now that I have done my research… First, how can a drug be prescribed to “regulate your period” if it will completely irradiate your body’s ability to even have a “real” period. Second, my doctor assured me that if I didn’t like the affects of this drug it would be out of my system in 3 months. She led me to believe that everything would go back to how it was before receiving the shot. We would then be able to consider other options for helping “fix” my painful and heavy periods. Also, not accurate. Now I have to suffer the affects of this drug. It has not helped with my period- just erased all of my body’s hormones and ability to even function. Has left me fighting at times with severe depression, heavy to light spontaneous bleeding, night sweats, a complete eradication of any sexual desires or emotions (well if you don’t want a baby there ya go) and vaginal dryness so severe that even if I wanted to have sex I am terrified of how that would go. This drug has affected mostly myself, but my poor family has been affected as well. My husband and oldest daughter worry to see me so unbalanced and often times fighting depression and my younger children have to deal with losing (hopefully temporarily) the happy balanced mommy they used to have. I would rather suffer the once a month painful hemorrhage like periods I used to have than have ever taken this drug. I will never trust another doctor again. They don’t empower women by shoving these synthetic drugs into us for a quick fix… We need experts to help us understand and learn about our bodies and to give us options other than synthetic birth controls to help us. I have done my own research- reading online articles and several books and I have learned that women do have so many options for preventing pregnancy or gaining hormonal balance (my period problems were obviously caused by an imbalance) that doesn’t involve the horrible side affects of such drugs. Do your research before going to an “expert” you will feel more empowered and will know how to sort through the “advice” your doctor will give you. Anyway, (in my experience) they will only give you birth control or destruction of your uterus as options. I know soon I will wake up from this nightmare and be myself again, but it’s going to be a long battle. Like another person said we just have to stay strong and positive and keep telling our story so that other women don’t have to go through this hell.

    • Changes says:

      I was on depo for 12years and I end up with a new doctor and she recommended I get off the shot. When I decided to have a baby it took me 2years to have one. But at the age of 35 I decided to get back on it and I’m having the most bad experience of the side effects. Night sweats, just sweating a lot during the day, bad cramps, abdominal pain, heavy bleeding in clots and nausea.

  116. Danielle says:

    Why does she his article not come up when looking for side effects of the depot shot. I think the tags of this should change to make it higher it the data. Before taking the shot for issues with cyst and fibroid my boyfriend and I researched possible side effects only found the simple watered down versions.
    I just skipped my last shot because I cannot take it anymore. I have been bleeding since June 2017. I will get a day or two off here and there. There are days that the spotting lasted so long the I would end up with a rash down there. I’m still trying to figure out if it was also because of a reaction to the aAlways Dailies. I had no sex drive, or if I did I was bleeding. Reading these comments confirmed every reason plus some as I why I stop the shot. I has even scared me be I had all the post shot symptoms during the shot. It seems as thought it is going to get worst.
    I work in a hospital overnights and I’m a full time student. I thoughts my anxiety depression and suicidal thoughts came from my busy schedule, but I think it was enhances because of the shot.

  117. stann says:

    I have never been an angry person. Usually if I get mad, I cry or just kind of shut down. This shot made me so angry that I saw red. Not anger, pure, unadulterated RAGE. Like I would fantasize about homicide and suicide and stay up all night so pissed off that I couldn’t sleep or do anything without being set off somehow. I’ve been on it 2 rounds. I have endometriosis, PCOS and PID. My doctors won’t give me a hysterectomy saying I’m “too young” (I’m 30), but I’m also trans, gay, and never want children. They are making me go through “every option” before they agree to this procedure. Honestly I’d rather be in physical pain than deal with this out of control rage. I’m starting to worry about suicidal ideation, just to make this stop. At least when I was in physical pain, I knew how to manage it. I would rather bleed for 2 years straight than ever have to deal with this again.

  118. Janice Shermer says:

    Why isn’t there a law suit against this drug? I have had many issues that I feel are associated with this drug.

    • Ms Margaret Smith says:

      I was watching a documentary last night about paedophiles in America and one of them said he’d been given it as an alternative to castration !! I couldn’t believe it, had to pause, then play it again. He was a man, obviously, but couldn’t believe my ears.

  119. Caroline says:

    After reading this website, I finally feel understood. Insomnia, non stop bleeding, hot flashes, night sweats, no sex drive and depression have been the story of my life since I took my first (and only!) shot a month and a half ago. I just wonder if there’s available statistics on how many women develop these side effects. How can health providers not be aware of them? Why recommend depo when someone can simply take a pill and stop it anytime? Can’t wait to be a normal person again and regain my life.

    • Monica Riojas says:

      Yes, me too and im in the same boat as you are in and i just took 1 shot about a month ago on February 21,2018 and i dont even recognize a my periods from all this spotting problems ive been having ever since , this is a monster injection !!!!

    • Monica Riojas says:

      Thats good , you know your body well before and after we start up on all this monster medicines and its your rights !!! Im going through tough times too after only 1 depo provera injection and im not the same anyone , i got the shot February 21, 2018 and im still having issues bleeding and all ?!!! Feel free to call me if you need someone to talk to or comfort while goimg through this tough time as i am , i am in houston tx. 346-228-1907 God bless you !!!

    • Monica Riojas says:

      My name is Monica , feel free to call me if you need someone to talk to or comfort while going through this tough times being on this depo shot as i am also , im in houston tx 346-228-1907 God bless you !

  120. Deannie says:

    After 15 yrs. of debilitating pain a laproscopy revealed I had Stage 3 Endometriosis. I too had women bosses that made my life a living hell because they were not sympathetic. The Pill made me violently ill twice so the recommendation was Depo Provera Shot, my period disappeared immediately. After being on it for 20 yrs I am now in menopause and have stopped taking the shots. For me and my body the side effects were easier than the once month pain my body went through. It was definitely the right decision, my quality of life was far more worse than without the Depo shot.

  121. April says:

    I have been on the Depo for nine years and haven’t had a period. Idk if this is healthy or not but I have broken both feet twice and looking at screws being placed in both. This can’t be normal.

    • April says:

      Bone density test are ordered. But I’m also told that no other bc would benefit me now that I have been on Depo so long and we don’t want more children I’m 42 urs young.

  122. Emerald says:

    When considering birth control, I was hesitant because I did not want to be the unlucky 1% who gets pregnant. I did not know about depo provera shot until after I had done my research on birth control. It sounded to be the most effective, least stressful birth control and I didn’t have to constantly worry to take the meditation at a particular time every day. I looked online for the pros and cons of this injection and I was for the most part satisfied. I was worried that I might get an increase in acne, body weight increase (but these were not the case). I had to get the shot after my period was done and the injection itself did not hurt at all. I am not bias, as I am deeply afraid of needles. It was honestly a pinch. I have had the depo provera shot for three months and I have been doing raw sex ever since, and I have not gotten pregnant. The biggest con and the reason why I am not getting this shot again is that I constantly had vaginal bleeding/spotting. I had to constantly wear a liner, and my partner was unable to perform oral sex due to the blood. I was self conscious of potentially meeting someone and them wanting to feel me up, and I would stop any chance of that happening because I did not want them to feel my liner. Also, I had heavy vaginal bleeding the day after I had sex. The pro of this injection would be that it is very effective IF you get the shot at the given time you’re supposed to, which is very three months. You do not have to be in constant fear that you might get pregnant.

  123. Monica Riojas says:

    Hi, im Monica and i am 38 years old , i have been on the depo shot for 1 month now after i discontinued with the IUD Skyla on February 21, 2018 , after 5 days of being on that injection i started spotting and then a heavy break through bleeding on February 25, 2018 that sent me to the emergency room. They did blood work on me and all and told me ot was tue side effect of swithing from iud to the depo provera and that i was fine and needed to wait it out so they put me on Motrin and blah blah !! So then the spotting never ended after that for up to 2 weeks and then i go to my doctor and he puts me on a birthcontrol pill ( Lo Loestrin fe ) to stop the bleeding/spotting and i took that and the bleeding finally stopped March 12, 2018 . Then i started getting all other side effects because of the birthcontrol pills and had to stop taking them on March 22, 2018 and then now we are still in March still and i start bleeding on the 28 and im not even sure if this is my cycle or what is it omg . Before starting any of these birth control methods i would usually have my periods on the 28 of each month and the latest would be on the 1’st of each month!!! But now i am totally lost and confused because of all this craziness that this injection has brought into my life i cant even tell what is a period or when or if its the bleeding side effect of this Monster Method that i chose ( Depo Provera ) . I clearly asked the doctor about what i need to expect along with this injection and he told me just the weight gain effect is all ? so i thought oh well i can manage that , and now i have to face all this bad things bloody mary and all until this monster medicine leaves from my system and i pray to god it will be soon in jesus name !!! I would not recomend this option for no one at all because you wont know what will happen to you until you’ve already put your foot into ot and then all the regrets start knocking at your door!!! This is the most scariest birth control ever !!!??

  124. Maryan says:

    I turned to be a different person after I’ve done the Depo shot. It’s disgusting, how you make money of it. I’m just losing my life, was thinking about suicide several times. It ruins my life, my school, job, friends and everything. I been depressed since I started the shot. I cant even stop it.
    Please whoever wants to take the shot, be w
    Very careful. It will destroy Your life. Trust me.

  125. Mary says:

    Im on the depo. & honestly this injection makes me feel dizzy, and weak at times. I spottted bleeding the first 2 month and now nothing. Ive put on alot of weight. I went from 125 to 160. I dont recommend.

  126. Ms Margaret Smith says:

    This contraceptive should be banned. I had extreme bleeding for months after stopping it and it took me five years to become pregnant. I also developed thyroid problems, which I couldn’t prove were a direct result of this, but I suspect it was. I have only one piece of advice for anyone thinking about having it administered… DONT

  127. Sarah Jones says:

    I had been on depo 10 years ago for about 5 years and decided to have a break, since then I’ve been on microgynon but then I started to have side effects from it so in Feb this year (20th) I had a shot…I was fine for 2 weeks and then started bleeding heavily with massive clots for about 7 weeks, as I write this I have had 2 ‘dry’ days so far and am hoping I don’t see a period for a while. I just started a new relationship so you can imagine this hasn’t been very good. He has been understanding though although I had to show him an article about the side effects because we had intercourse one night when I u thought it would be safe and when we finished there was blood everywhere, I was so embarrassed. My next shot is due in May and I am thinking of not having it just in case same thing happens again.

  128. Bill Chaffee says:

    I’ve used a number of different oral and injectable hormone preparations because of gender dysphoria. I prefer bio identical horomones. Natural estradiol is normally taken by injection because most of it is destroyed before it gets into the blood stream if taken orally. Ethinyl estradiol is a synthetic hormone which is effective when taken orally and is associated with blood clots and other serious side effects. Provera is a progestin and is not a substitute for natural progesterone. Other people that I’ve talked to don’t like Provera it either.

  129. Rere says:

    Getting on the depo shot was the worst decision I ever made…..doctor told me I have to get on some kind of birth control because I can’t get pregnant for the next year I suffered a partial molar pregnancy in February and got the shot in march. in April I started getting constant bleeding spotting and heavy bleeding for weeks and it still hasn’t stopped! I Have mood swings and depression and weight gain and literally lost my sex drive .I only got 1 injection and noticed such a huge change in my body. I told my doctor about all the symptoms I was having and she just told me to try getting another shot early and maybe the symptoms will go away…I will never put that stuff in my body again I regret it so much!

  130. Sky says:

    I didn’t read anything about reversing all or any side effects. For all women young and old that it is too late for, what are they to do?

  131. Amber L Blanchette says:

    I was on the depo shot when I was younger and don’t remember my side effects being as horrible as they have been for me this time around (I am 39). Loss of sex drive, I am like a desert down there, I’m exhausted, I get headaches, am moody, I feel as if I am going crazy and I have serious cramping issues. I didn’t get my next shot as per my doctor due to my serious side effects and I feel as though they are worse. I haven’t stopped bleeding, I am very bloated and have gained 10 lbs in 3weeks, I have not changed anything… I simply don’t know what to do.

  132. It was during the time I took Depo-Provera I gained about 10 lbs and couldn’t get it off. I also feel that something happened to my colon or gut, because from then on. Almost 20 years I have had loosebowel movements. I took a lot of stool tests but nothing was ever found.

  133. Amanda says:

    I was given the Depo Provera shot after almost exhausting all other methods of birth control to help me with endometriosis pain. I too will say, if I could go back and decline this method of contraception, knowing all I know now I would. I took the shot out of desperation for healing from pain of endometriosis. Although the shot has worked for the endometriosis. My quality of life has gone downhill times 100! Each time I’ve gotten another injection a new side effect appears. I have also been to the point of anxiety where I feel I am going insane. I have reached a point where I was internally reviewing life and it’s point while on this shot. I have extreme joint pain, experience low sex drive, weight gain after working out my hardest only to feel more joint and muscle pain, bladder issues, moodiness, and insomnia! When the shot wears off I always consider not getting another. But then my estrogen skyrockets and I experience extreme PMS to the point of insanity! I have body aches, nausea, more insomnia, muscle aches, increased sebum in my skin which causes studs in my eyelids, pain again in my pelvis cysts, and sometimes migraines. It is a freaking nightmare. Which sends me down the path to ask for another shot because I cannot hate the side effects. But each time I go through this cycle it takes a larger chunk out of my soul! I feel helpless as to what avenue of approach I should take because on the beginning I think I had an estrogen dominance that was causing me cysts and endometriosis but now I’m much worse. I would have also rather been pregnant 15 times over then go through this it’s been habilitating to say the least. I’ve read comments where ladies are saying don’t blame the doctors or it helped keep you from getting pregnant! I’m sorry to tell you, I personally fought my doctors on every whim about taking this and other methods and rather instead approaching the problem. I was shut down on every occasion! Every! My complaints pushed under the rug and denied, and for those women who have taken this and were not informed and simply took it only for pregnancy are being just as punished when they go to have a baby and cannot because they cannot get back to their usual cycle or are suffering from life altering side effects. You cannot put this on the woman. This is not her fault. I cannot understand how you go to the doctor and it’s supposed to be about choice but these things or medications are shoved down your throat with no option for escape! In my case I’m angry, feel helpless and a littl psych that I have to drag my tired and hurt body from the bed to try and make it through another day like this. It’s unfair and all I can do is keep hope.

  134. Jules Pitchford says:

    Today I don’t even know where to begin. I had an idea that depo wasn’t the safest option but until last night, I had no idea that it was the reason for living in my own personal hell.

    I started taking “the shot” when I was 16 to relieve severe symptoms from my period. At the time it was a gift from God. And once I became sexually active it was killing two birds with one stone, what’s not to love?

    Had I known then, what I know now…every single morning I wake up to pain coursing through my body. Love the idea that now I will wake up with pain on top of the remorse and regret that I had done this to myself. So now what?

    I have been to hell and back trying to explain my deep, unrelenting, constant pain to doctors who eventually saw me as an “addict”. I started to believe them and admitted myself to two failed attempts at rehab. At this point I saw no reason to continue with life. If it weren’t for my boyfriend I would not be here. With his help I was able to detox and move on with my life and it’s been a year since I have taken pain killers. Although I’m very proud of that, I still desire that feeling of pain melting away and then getting on with my day.

    Yesterday I shared with my boyfriend that I had been crying all day, for no reason other than I must be getting ready to start my period. But this time was different, I felt empty, alone, worthless, and hopeless. He started doing research, asking more questions and we came to the conclusion that everything I was feeling, physically, mentally and emotionally was because of the depo.

    I am devastated. I no longer have insurance but even if I did, I wouldn’t know who to ask for help. This has to stop…this poison should not be available to women of any age.

  135. Jennifer Green says:

    21 years ago when I was 15 my mom took me to get birth control and we picked the shot because it was more reliable than the pill for an out of control teenager with a history of running away. It majorly affected my mental state. I was afraid of being raped by every man I came across and I was also scared that I had the potential to be a rapist. I Was barely holding it together. When the Depo shot wore off I had a period that seemed to never end, two or three weeks. Finally I went to the doctor and I was given birth control pills to make the bleeding stop. When I felt as though I was losing my mind I did what research I could on the Depo Provera shot, this was pre-internet, and found that it should not be given to anyone under the age of 16.

  136. Brian says:

    Could anyone Please recommend a doctor in Chicagoland or the Midwest that is familiar with these issues? My wife and I are so frustrated with doctors that just say that depo has no post use effects and end the discussion there. We are dealing with some bad effects and have become somewhat hopeless until we read this article. Please help.

  137. Anna Geck says:

    It was the early to mid 1980’s. I thought I was doing the right thing to stave off the effects of endometriosis. The doctor encouraged this treatment as the newest thing for endometriosis. I bled, I bloated, I had dryness, acne, and I was encouraged to continue rather than face the debilitation of endo. By 1985, I had a complete hysterectomy. In 1987, the nausea became worse, and in 1988, I was told my colon had collapsed. Whatever was happening to me emotionally during the course of treatment that ended in 1985, I was alienated for life from family and friends. Everyone I spoke to just thought I was a slacker during the period of time I was on this drug. I have never had any lifestyle habits like drugs or alcohol. I can’t believe this drug has continued to be available. The information I am seeing for the first time all these decades later has, at least, verified what may have been the culprit to a very dark and unforgiving time in my life. I believed when accepting this drug treatment that I would be preserving my reproductive system.

  138. Pingback: 1,000's of women experiencing Depo adverse reactions - Holy Hormones Journal

  139. Jenn says:

    The depo shot almost destroyed me. It took me 8 months to realize what was wrong with me. I haven’t taken one now in 7 months and I’m still not over it. The one and only time in my life I felt suicidal:( I wish I had known more about the shot before I took it. My main reason was to stop my bleeding. I just wonder how long until I feel I am back to myself again?

  140. Corrie schnepp says:

    I have been on the depoprovera shot for over 20 years. I had to go on it in order to stop my periods. They were so bad that I actually became anemic from them. I would get my periods for 3-31/2 weeks and I would get a week as a break and then boom it was back. My periods were very heavy and my obgyn ran tests to see what was going on. I started getting my periods when I was 10 years old. At 13 or 14 my obgyn tried having me on the pill but that didn’t help me. I still got my horrendous periods on the pill. When I was 15 years old i had reflux surgery and I couldn’t take the birth control pills because they irritated my stomach so I talked to my obgyn about the depoprovera shot and I have been on it since then. I don’t plan on having any kids. I was told by my obgyn when I was 15 years old that I would have a difficult time getting pregnant and holding a pregnancy. I was told I would have to go on fertility drugs if I wanted to get pregnant but with what all my body has been through and with my multiple sclerosis I know that it is not a good idea to get pregnant. All I can say is that the depoprovera shot has helped me and with me going through premenopausal it’s helping me with that.

  141. Emma aston says:

    I’ve been on the depo for 2 years now, I was 12 stone, fit and healthy, and happy, in the two years I’ve gained 4 stone, I’ve lost my sex drive, I’m moody / depressed…. I suffered with insomnia, now I’m so tired to the point I could fall to sleep standing up sometimes!
    I feel drained
    No concentration
    No motivation
    I decided today as I’m due my next shot to come off the depo and the doctor has gave me desogestrel, the side effects are as bad….
    I’m not off the depo yet I have one week before it runs out…
    I’m afraid now, I don’t know what to do.

  142. Lindsay says:

    Is it possible for depo provera to aggravate PCOS symptoms or give you PCOS? I was on depo for 9 months and I’ve off it for 5. My gynecologist recently diagnosed me with PCOS because of my irregular periods, abnormally high testosterone levels, and pelvic pain. My periods before depo were heavy but only lasted a week. Now my periods last 3 weeks and I have to go to the chiropractor once a week for pelvic pain.

  143. Hannah says:

    I’m 19, and will be 20 in December. I got my first Depo Provera shot a little over a month ago. I had had incredibly irregular periods (once being 3 weeks late) and being on the pill a few years ago didn’t help very much. I was considering the arm implant but I was strongly talked out of it by my mom and my aunt. My mom after she had my older sister was put on the shot and she loved it. She got on it right after my sister, bled for two months straight (postpartum bleeding catching up for lost time haha) and she didn’t really experience any side effects. Her and I are both prone to migraines and since that is a common side effect I asked her about it and she said she didn’t get any. My sister and I are a little bit over two years apart and she had no issues getting pregnant with me after (she told me she got pregnant with me 9 months after getting off the shot so I’m not sure how long she was on it). I was ecstatic so when I was home from college I saw my doctor and got on the shot. She tried to talk me into the arm implant, or the ring, but since my mom had such a great experience on the shot I was adamant. I got the shot on what was supposed to be the second day of my period (again very irregular, almost always at least a week and a half late), and was fully prepared to spend two months bleeding like my mom did. At the same time I got the shot I got back on Prozac because I was noticing my mental health going down hill again.

    When I got the shot I hadn’t had sex in almost two months (my boyfriend leaves the country during summer break) and my pregnancy test came back negative.

    About a week and a half or two weeks after getting on the shot I started spotting. It was pretty much black which did concern me. A few days before that I started getting a lot of vaginal flatuation and I had been very sensitive down there. I’m talking sometimes wearing underwear is uncomfortable. I emailed my doctor and she said spotting is pretty normal, knew nothing about why the flatuation was happening, and didn’t respond on the sensitivity but said I may need to look into another method and that if the issues continued I may need to come in for an exam. I told her I still thought it was the best method for me and figured my problems would go away.

    I think it was three days after the spotting started I had the worst cramps of my life. I took pain relievers, and used a heating pad but nothing helped. When I had to stand to do something I was doubled over and in tears. I’ve had very bad cramps in my life but nothing like that. It was awful. Then I sort of thought it seemed like contractions. They were spaced apart and lasted a certain amount of time and I tried to breathe through them. I ended up going to sleep and at 4ish in the morning woke up to use the bathroom. As soon as I sat on the toilet this huge thing slid out of me. At first I just assumed it was a blood clot and then I realized part of it was a different color/ texture and again it was 4 in the morning, I was sleep deprived, and ended up panicking myself into thinking I had a miscarriage. I took a picture to send to my doctor and shot her another email. At a more appropriate time I ended up texting my mom freaking out, she had me explain and told me she had the same thing happen when she was on the shot and it freaked her out too but it was just the uterus shedding it’s lining and trying to get rid of everything that’s been built up in there to stop periods or make them lighter. When my doctor emailed me back she didn’t even explain what it was, just said it was common.

    I still have increased sensitivity, I’ve been spotting for two and a half weeks now, I randomly get very bad cramps, and I still have the flatuation. I haven’t had another huge thing slide out of me but reading this has made me pretty paranoid. Has anyone else had these experiences? What was it like when you stopped getting the shot? Or did you keep getting it and your issues resolved themselves? Again I am only 19 and really don’t want to have a lifetime of issues for trying to protect myself against pregnancy while I’m still in college. Any advice/ insight would be very helpful. (And before anyone says use condoms my boyfriend and I do. But condoms can break and fail so I wanted to be extra protected.)

  144. Brittany Saunders says:

    It’s so strange, any time I looked up people having infertility issues from the shot I never really saw anything…
    I took depo, I think I started in 2014-2015 because my mom thought I was having sex ( I wasn’t, I was 15) and I took it till I was 19 . I had a period for 6 months, and then nothing it went back to normal other then my period becoming horrendous puking passing out from the pain, still happens to this day. I have never used a contraceptive with my husband I’ve been with for 6 years and not once have a even been concerned about getting pregnant. I just assumed I was crazy to link the two and just thought I just couldn’t have kids. It’s been 9 years since I’ve taken Depo Provera last. It has made me completely infertile.

  145. Diana L says:

    I was on the Depo-provera at the ages 25 to 30 and never had a problem. I then stopped taking it and didn’t have any problems either. I am 38 now and first got the shot again in April 2018 and I did get some headaches and a lil rash but I thought it was a different medicine I started taking. So I got the shot again in July 2018 and the rashes came back full force. Every week they get worse. I have headaches dizziness discharge. I am tired all the time. More anxious and angry. Gained weight and bloated all the time. I have acne all over my face and back. This the worst experience and I will never get the shot again.

  146. Diana L says:

    I was on the Depo-provera at the ages 25 to 30 and never had a problem. I then stopped taking it and didn’t have any problems either. I am 38 now and first got the shot again in April 2018 and I did get some headaches and a lil rash but I thought it was a different medicine I started taking. So I got the shot again in July 2018 and the rashes came back full force. Every week they get worse. I have headaches dizziness discharge. I am tired all the time. More anxious and angry. Gained weight and bloated all the time. I have acne all over my face and back. This the worst experience and I will never get the shot again.

  147. Keya Foley says:

    I am only 21 years old and i’ve been on the shot for almost 3 years. When I made my OBGYN appt, I was suffering from severe menstrual cramps, really heavy bleeding to the point where I was nauseous and weak. The Dr. told me about the “minor” side effects, but didn’t tell me about the “major” ones. I was simply blinded by the fact that I wouldn’t be in pain anymore, that I risked my memory taking a hit. I’ve been very forgetful lately. I am extremely tired and depressed, I cry all the time, my partner and I are having more arguments than normal. I have a lower libido/sex drive, which made me realize something was wrong. Like the other ladies are saying, these young girls out here, like me, have no idea about how our bodies are supposed to naturally work. So we jump at the best ideas we believe will fix our bodies’ “problems”. This shot has affected my relationship at home, at work, and at school. I found this blog to be very helpful in my decision to get off BC forever!!

  148. Brenda Cabral says:

    I 💜’d my depo!!!!
    I was on it for 10 yrs.
    No period at all… so no ovulating.
    Doctor suggested I get off after 10 yrs. because it may start a decline in bone strength. So I got off. Took about 6 months for periods to return, like clockwork now.

  149. Jessika says:

    I got my first shot in July of this year, and since then I have bleed non stop, mood swings like crazy. The horrible side effects of this birth control are definitely not worth it in the long run! I totally regret ever having this injection! I’m angry at myself and at my doc for not advising me of the possible side effects!! This form of birth control should be taken off the market!!!

  150. Alexandra says:

    I just had the shot and when the nurse put the needle in my hip to inject it the liquid exploded everywhere. 2 hours later dealing with manufacture and insurance just to end up paying full price out of pocket for another one. Hopefully to be reimbursed by the company in a month or so. Good start right ladies.. The nurse put the second go at the injection in my other hip. The side where she messed up the first time is so achy and sore. The second injection went in fine and has no soreness.

  151. Ana says:

    The person who said “rejoice that you did not get pregnant ” not all women are on the Depo to avoid pregnancy but to slow the development of endometriosis and ovarian cysts like me. However I have been on this medicine for a while and one big thing is that for 2 weeks after getting the shot I’m horibly Moody my family wants nothing to do with me. Then for the rest of the 3 months until my next injection I feel numb to everything but this crippling depression. I find all the things I had enjoyed before depressing and they aren’t fun anymore. I am going to try the pill again but I’m running out of options and they didn’t warn me about the perimenopausal symptoms you can experience including hot flashes even when I ask my pharmacist what I needed to know and what other side effects are rare but can happen. I wouldn’t recommend this to anyone. I used to be a social person now I want to just lay in bed and the littlest things send me in to a pit of despair. I already have an auto immune disorder and I’m very sick this depression is making everything worse

  152. Infertility says:

    Like most of these women I too have been a victim of Depo proverb. When I first got my menstrual cycle; I had soo much pain. I was 15 and the first 3 days for years were horrific. My Doctor would prescribe medication to help me cope with the pain every month until After about 2 years. The nurse called my mom because they knew I was going to be coming in once I started my cycle for the month. My mom took me to my doctor and he talk to us about this new medicine that would “help with the pain and I would miss all of the school” that I did. I hate needles so as soon as he said a shot every 3 months tears start flowing but he and mom as naive as she was assured me that it would be ok. Needless to say I was astounded at the fact that I had no cycle and over joked that i wasnt in pain anymore. Well from age 17-25 I was on these shots. I met my boyfriend at 21 but wasnt sure if he or I wanted kids at that time. I was still in school and we weren’t ready for marriage just yet. We decided that after my 25th bday we would wed and we also decoded we would have children. As far as I knew. I could still conceive because the depo wouldn’t make me infertile; as I was told by the very doctor that first administered the shot. God was he wrong. After 3years of us trying to conceive and test after test on both of us we decided to not go on with it. Not just because of the physical exahution but emotional as well. I am now 35. I have never been pregnant and I am medically capable to carry a child. The only thing my OBGYN can say is that my only option would be invetrofertalization. I was told because I was on the medication for so many years it could had adverse side effects on my reproductive organs. Even though I have a cycle every month that doesn’t mean that I would ever be able to conceive the quote “old fashion way”. I long to have a child on my own. I have two younger sisters that were afraid to tell me when they were pregnant because they didn’t want to hurt my feelings. I hope my story helps someone.

  153. Jacquie Amos says:

    I just got my first shot early this month and am already experiencing major headaches, mood swings, eating alot, no sex drive etc…

    Hence I have decided to not go and get my second shot in November after reading all this negative comments from women who have experienced much worse than I have over the years. What I’d like to know is ‘what side effects there’ll be when I stop getting the shot’….

  154. B-L. Luna says:

    I am amazed by the number of women out there complaining about the side effects of the medication they experienced after the fact. There has been tons of information available about this medication for years. I can’t possibly understand why anyone would be okay blaming someone else for affects they experienced as a result of a decision they ultimately made for themselves. If the information regarding this medication was not available that would be an entirely different story. The fact is the information has been available for years and so many people for whatever reason chose not to do their due diligence in researching the information. Such a shame.

  155. Lindsay says:

    Thank you to all the strong women who shared their testimony about the Depo shot. I decided to not take my first shot. Instead, I will start the birth control pills to treat my condition PCOS. I pray that your health will be restored and renewed strength from God. Xoxo.

  156. Lee Kohls says:

    I had taken the shot a couple of times worked well. I had severe endometriosis. Had 3 d and c to see it would help. They did not work. I would sometimes pass out from the severe pain. Next time I took the shot I had my cycle so bad. I got very depressed
    My cycle lasted 5 months I had to get my uterus removed. The depression was so severe I had to go on medication
    I had to change clothes 2 or 3 times a night from sweating so much. I wouldn’t recommend it to my worst enemy.

  157. Johna Charles says:

    none of these articles state the age of the person going off the depo shot. i am 53 and i want to know if my estrogen will go back up. my blood tests show i am post menopausal. i am wondering if my hot flashes are so bad because of me being on depo. i would like to see articles of women my age and what happens when they come off of it.

    • Michelle M Meteyard says:

      Hi I was on depo for 21 years..I am 47 and went off of it 6 months ago..I got my period 4 months after I stopped and then it was confirmed i had in fact started menopause. I worked in the medical field for 22 years and I’m pretty sure depo provera isnt the hormone used for post menopausal women. I think its straight estrogen. I would ask the doctor.

  158. Theresa says:

    I had the depo shot three times and stopped after that as it made a huge dent in my leg like it ate my muscle. It is very ugly to look at. I won’t wear shorts anymore. It has been a year and it has not gone away and I’m not sure it ever will. I showed it to my doctor and the the response I got was “that is weird . I have never seen the depo do that. I was experiencing excruciating back pain and non stop bleeding with this drug, and after I stopped taking it I continued with months of misery and abnormal periods. I’m not happy about this drug at all.

  159. Shelby says:

    All the sudden I’m getting easy brushing and I’ve noticed that it’s gotten worse since stopping my Depo shit. It was like it wasn’t there and then a week or so after my time to get the shot I started brushing and it’s only gotten worse. What can I do? Blood test comes back with vitamin d deficiency and it’s scaring me that it did irreversible damage to my bones and effected my blood cells and platelets

  160. Sheila Botelho says:

    My 19 year old daughter has been taken it for a year. That’s the only shot of any kind or medicine of any kind she has taken. Last week she went to walk in clinic and had a little rash on the inner part of her boob. The physician told her it looks like inflammatory breast cancer. We have no cancer in our family. She doesn’t smoke or drugs or booze. This doctor better be wrong. I was wonder if anyone else had cancer from the depo.

  161. Sheqo says:

    So glad l came across this article. I used the shot 4 years ago and noticed my bones had become weak because l easily fractured which isn’t normal for me. I also suffered mood swings and depression. Recently l decided to try it one more time incase it wasn’t the culprit. I was doing some research about it and boy oh boy, l will stay away from Depo-provera shot. Thanks for sharing

  162. Shannon says:

    Caya diaphragm, updated silicone version, not the old discontinued style. Most doctors are clueless about it and push hormonal bc. We DO have options. Caya and condoms = no baby. No condom, no sex, the end. Take care of yourself 1st ladies.

  163. Michelle M Meteyard says:

    Wow !!! I read all the comments. I was on depo provera for extreme uterine fibroids and was unable to have any children. I was on the depo shot for 21 years and stopped 6 months ago because I’m 47 now and wanted to see if I started menopause. After 3 months I started having normal periods and nothing abnormal. I am definitely blessed.

  164. Sarah says:

    You are skipping over one very important act – that Depo Provera is a first choice treatment for women with endometriosis and allows many of us to live lives as close to pain free as possible. I currently have no active disease because of Depo, and as a woman who wouldn’t be able to have children anyway, Depo is the reason I have any quality of life. Please don’t vilify a drug outright without looking at who might be benefiting from it as well. I was told if I ever wanted to come off Depo I would need to be on a progesterone only pill for a year and then back off the hormones slowly. Of course withdrawal from a high dose hormone is going to cause side effects! If women aren’t going to educate themselves about what they are putting in their bodies they can’t expect anyone else to be advocating for them.

  165. Isabel Chang says:

    I never myself used Depo-provera, but I was in Kenya when they were testing it on the poor Africans there, in 1984, of course not mentioning side effects or showing illiterates written info in languages unfamiliar to them. Big Pharma is real. I was a test subject for Fansidar, in Canada, as a student. Slimy lot these people who create and sell these poisons.

  166. Grace says:

    I’ve only been on the depo shot for not even 3 months and these have been 3 of the worst months ever. I’ve been living with frequent stomach cramps and sharp stabbing pain, there’s times when I feel that nauseous that I’m bed ridden for days, I’m losing way more hair then I use to, I have constant headaches and my eyesight has become worse, I’m irritable and I swear I’m always yelling at people . That’s just a handful of what’s been going on, I honestly wish that I never got it.

  167. Nanaa says:

    Depo was the worst for me . I only got it once my period changed . I bleed heavier than I already am , I get my period 2 times a month . I only stay off my period for literally 1 week and after that I get my period again for another 2 or 3 weeks and it starts all over again for months and months . I was almost 90 something pounds last week about to hit 100 pounds . The next week I’m 70 something pounds .. this been so depressing for me and it’s crazy . I rather get pregnant than use this depo honestly.. never again ever!!

  168. Shianne says:

    I took the Depo-Provera when I was 17. We couldn’t afford the hormonal IUD (Kaiser didn’t cover it) so at the same appointment I got the shot. Once my periods stopped I didn’t enjoy missing the NATURAL security that my body was healthy.
    I quit after the first shot. TWO YEARS later my periods are finally a little better. I had EXTREME; mood swings, huge clots, and very sore breasts, menstrual being 8-10 days long continuously HEAVY. All of these were problems from stopping it. Also, my periods were a 28 day cycle like clock work.
    Since then I’ve been a 35 day cycle on average. DEPO FUCKED ME UP! I want to be pregnant some day. I hope the shot didn’t ruin my chances of starting a family after college. I never would’ve taken it knowing the other possible effects. I’m the person that decides to be safe than sorry, but I’m not a virgin either.
    I don’t trust BC anymore. I’ll let my body do its thing because DNA is literally biological instructions passed down and it has worked on its own.
    Why mess it up? Doctors are suppose to look out for us. Maybe there’s a bigger plan in progress here. I believe Depo-Provera is to make women infertile to alleviate the issue of our high population.

  169. A. Smith says:

    I first took depo when i was 17 til 18 then 19 i had my first of five children. I bled continuously after my first shot but after my second shot ot stopped an did not return til after i stopped taking the shot. Growing up with painful and irregular periods i hated the first 3 months of it but it was so freeing not having to buy tampons, pads, have horrible cramps like i had to before. True the first 3 months after the shot was bad but it was so worth it in the end. Now I’m 20 years and 5 children wiser with my youngest being months old getting my 2nd round of depo in days and it was just like i remember it back then. The bleeding subsided a couple weeks ago an of course i was doubting my decision beforehand but like most things it just had to run its course.
    Took it, bled bled bled, stopped an never started til i stopped then had kids…lots of kids lol. No health issues, all my kids are perfect and i was already fluffy 😊 My point is, i do recommend the depo shot especially if you don’t want a period, PERIOD

    • Trista says:

      I am being forced to get the depo shot by my mother. I keep reading all of these negative things. I want to have kids in the future and I don’t want this to mess it up. and I also do NOT want to bleed nonstop like a lot of people are saying will happen when you stop the depo shot. Should I be nervous, should I try to talk my mom out of it?

  170. Wanda says:

    My 21 yr old daughter received a Depo shot, HPV shot & a flu shot all at the same time in January. She has been constantly ill with upper respiratory infections & colds that last beyond a month I am afraid that she might get pneumonia. She has been bleeding ongoing non-stop, it may stop for 3 or 4 days then she will continue to bleed for 3 to 4 weeks she was a 146 lbs now she weighs 115 I am watching her dwindle away right before my very eyes. What can I do to get her healthy again, will a low dose birth control pill stop the bleeding. I think that the ongoing bleeding has weakened her immune system. She had to quit her job. She did not consult with me before this happen, she had never been on any type of birth control before. She has never experienced any weight gain only continued weight loss due to all the heavy bleeding. I was out of state on a work-related project, she never had any prior issues with her health. She only went for a yearly physical when they talked her into getting the Depo, HPV and flu shot all at the same time. The doctors told her she by bleed for up to a year and it has been 10 months. She is very fragile week & constantly ill, she has become angry with a lack of appetite. Can someone give me advice I am afraid & concerned re: my daughter’s health

  171. Ofelia says:

    I need help and i dont know where else to go
    I had my depot shot on August 3 and after august 15 i started to feel nauseated my breast are sore basically all pregnancy system but i have taking 4 urine test and one blood test and they all negative could i be pregnant and the depot shot affect my result or can my pregnancy be only in my head please help

  172. Blanca says:

    Depo…I decided it was the” best and quickest” option after my postpartum checkup. I believe it was the worst idea. I have been depressed at times where I cry at the most random things.very low sex drive.. literally have to force me to concentrate because it’s so hard to focus. Once I focus it’s fine. but I do feel bad that husband has to try so hard for me to get interested..other problems…I had a fight with my mom and then I message her saying I’m sorry and next I’m outraged because I don’t have an answer right away!. That is when I noticed that wasn’t me. I try to calm down and talk my self down and try to not go off on people. I am sure it’s the depo shot. I also lost a lot of my hair. It’s horrible how this shot is given without letting you know exactly what can happen. I was trying to do my hair to head to the fair and I burst out crying because I was trying to hide my bald spots. I suffer from insomnia and I can never catch up on my sleep. I am always tired even if I do sleep. I am currently taking omega 3 and biotin and I actually feel a little more active but will definitely stop depo.I took the shot in September.. and I’m due November 12th but I already set up an appointment this month for an IUD with no hormones. I used it when I had my daughter and it worked so I’ll go to what I know. I tried IUD with hormones and I had terrible migraines and cysts in my ovaries. So apparently me and hormones from contraceptives are not compatible. I really hope more people come forward with the problems they are having.

  173. Holly says:

    I started Depo for horrible PMS, periods, cramps, mood swings, etc. First couple of years, it worked great, lowered symptoms. Lately I’m having progressively worse IBS symptoms, increasing headaches, abdominal cramping, some rectal bleeding, and other things of concern. I have a very stressful life (live-in caring for two elders with dementia) and a metabolic problem. I can’t tell if these recent symptoms are related to Depo or “just” to stress and aging (early 50s) and possibly peri-menopause. I can’t afford to gain more weight because at highest weight I was pre-diabetic or to have suicidality, etc., because I’m a primary carer and with depression and anxiety since childhood I’ve worked damn hard to leave those symptoms behind. Please tell me there is at least a chance that I can quit Depo without having all these terrible effects. I’ve treasured these few years without cramps and horrible bleeding and raging mood swings and I do not want to return to those problems, now or ever. I didn’t know birth control could cause gallstones, and I had my gallbladder removed 20 years ago, now wonder if I’m having Depo side effects or bile acid problems, who knows? It’s very frustrating when no doc will admit that BC meds can cause these side effects, including weight gain, which I now find is a huge reported problem with Depo, tho I was told it should not be affecting me that way, and all docs seem to think all my problems are “merely” stress related, like it’s easy to manage stress when it’s 24/7/365. I want to keep my sanity AND improve my bodily health. I also don’t understand: what is the difference (if any) between BC hormones and “bio-identical” hormones and should I pursue the latter? Thanks!

  174. Anonymous says:

    I started the depo shot in 2013 and got off 2016. As soon as I got my first shot my sex drive went completely away 100% and ruined my relationship. Everything went downhill and now we’re back together now but I still have no sex drive and it’s been 2 years since I’ve been off of it! I am desperate for help. I want my old self back. Will my sex drive come back at all?? Has anyone else experienced this and did your sex drive come back ?? I’m trying to stay positive but starting to lose hope that I will never be able to satisfy my boyfriend the way I naturally did as BEFORE I got on birth control.

    At this point I just need someone to talk to about this. I keep it to myself, it’s just embarrassing. I lost my sex drive at 17 and a half years old and I’m now 22 and feel like I already have been through menopause. I just don’t know what to do or how to feel. Someone please help me

  175. Kendall says:

    I have taken the Depo shot once, back in March of this year. Since then, my periods have been so abnormal and I’ve experienced weight gain in the worst areas, which has been concerning to me since I have been a tiny person all of my life. I read all of this because I didn’t know if any of this was normal. But I guess it is?

  176. Roxanne says:

    I don’t think that anyone of us is arguing that Depo Provera hasn’t fulfilled its purpose of preventing pregnancy or that there aren’t other birth control options available. However it is unfair for persons to trivialize our experiences. I work in sexual and reproductive health for over 14yrs and I know how depo provera works. My knowledge and insight of the method by no means prepared me for the horror story that’s now my life. The bleeding!!!! OMG totally affected my self confidence. You’re never sure when you’ll bleed. During sex, after you pee, sitting at your desk and just feeling a warmth; just spontaneous bleeding. It’s awful. I have experienced every side effect listed for this drug… EVERY SINGLE ONE. I’ve been off depo now for three months after only having 3 shots. I am no way relieved of the side effects. Nothing has changed. Reading this blog made me angry because Depo Provera continues to be considered an approved birth control option with new acceptors (victims) every day. I want to add my voice and make the conversation louder. Depo Provera should be recalled.

    • Malorie says:

      Ive had the shot twice, the first time i had it, the first two months were okay. Its the last month that REALLY gets you. I wouldnt know when I would bleed, because the first two months, i didnt even spot. The abdominal pain is absolutely awful, to where I can’t get out of bed somedays, and can’t sleep at night because my body is just weak and hurting. There’s been times where I really was convinced me dying, would be better then having to deal with this pain. But it got so bad, i got hospitalized. When I told my obgyn about the symptoms, she brushed it off like it was nothing, and said the second shot won’t be anything like the first. WRONG! The second shot is 100x worse, when I got the shot I weighed 127lbs, i now weight 105lbs. I throw up because of the excruciating pain, and can’t even eat somedays. The shot is awful, and this round is the last rpund of ANY birth control I’ll ever take.

  177. Rose says:

    Hi, I have been bleeding nonstop since March 2018 after the Depo shot. I was aleeady anaemic and taking iron injections regularly before depo. I was prescribed depo for pelvic pains. Dr’s prescribed this assuming I had endometriosis. Now I bleed nonstop and it’s affecting my work and social life as my working hours doesn’t permit more than one break in the morning and afternoon and an hours lunch. So I can’t use the loo too often to change pads. Please let me know if you manage to find a solution 🙁

  178. Irena says:

    I’ll be honest, I read these before the shot and was terrified.

    I used to have no control over my hormones and often ended up suicidal with a few attempts under my belt due to lack of hormonal control with no actual solution due to what the issue was. I dealt with major depressive episodes and struggled with other various mental health problems. I also started having chronic, hospital-inducing Migranes in High School that followed me up until I got the shot. I also was on the border of being diagnosed with an ED because of my weight despite eating 4-5 balanced meals a day to try to gain, and I dealt with IBS symptoms on to of that, which made my Endo and heavy periods worse if an episode triggered during them.

    I tried the pill growing up, it never did anything for me, and I tried 7 different types both brand name and generic. One of them made my period lighter and cramps slightly better, but I lost more weight on it and I was constantly lethargic so I immediately went off them.

    Then, when I went to my first PP appointment, I decided to use the shot while I decided on if I wanted an IUD so that I would have some form of protection, since when they tried to insert it they found out I’d need to be put to sleep.


    My only issues is my bone density, which is probably the cause of my carpel tunnel and my knee issues.

    Everything mentioned above with my past problems is either on a minor and manageable scale, if not gone at all, and that all changed after about a week on the shot. Nothing every really helped before, it literally changed my life.

    Stopping my period stopped the majority of my IBS episodes and regulated the hormonal imbalance that I’ve had since I was a kid, and helps me manage my BPD and Depression, which makes PTSD triggers way easier to handle. I’m now a normal weight for my age, less lethargic which is making me active, and my boyfriend even said when I started it I actually started wanting it more often than he did. My migraines only have a lack of sleep trigger now, which is pretty easy to avoid, when they used to happen if even a light flickered in a funny pattern, still hospitalizing when they do come on though.

    It’s not for everyone by any means, and I don’t know what the effects will be like when I’m off them long term (I missed this one by a week and I’m having withdraw symptoms admittedly, so it’ll be a long process if I decide to come off them, I currently don’t plan to, probably similar to when I moved out of the C8 water, since I had a very similar reaction.) But in the now, it’s the only reason I can properly function in the day, when nothing else could help.

    I thought I would put out my current experience to tell people what it can do, and the adverse effects I’m already dealing with. There’s pros and cons to everything, it just depends on if you want to deal with those pros and cons, and it’s always best to research beforehand.

  179. Malorie says:

    The depo shot has to be worse than giving birth. The pain I feel from it, id MUCH rather had 18 kids right now. Depo is the worst possible thing anyone could do to their body, and I wouldn’t recommend it to even someone I hate.

  180. Leah says:

    Hi I’m 16 years old and have been on the shot for about a year and I’m just now experiencing the side effects.. My stomach pain is unbearable, there’s a feeling of fullness in my lower abdomen, I’m nauseous, dizzy, tired, and my breasts have gotten smaller and my bones are weaker.. My anxiety awful, I’ve begun to think i’m pregnant because of the side effects!! I’m very active and play many sports and have seen a huge difference in my body since taking the shot.. Worst experience ever.