The Very Early Perimenopause: What We Can Learn from Dr. Jerilynn Prior’s Research

By Nina Coslov — November 25, 2019

In my early 40s, I started noticing changes in my body. A once great sleeper, I was now waking at 2 a.m. – often with lots of energy and sometimes with anxiety. I’d be awake for about 3 hours before I could get back to sleep. Around the same time, premenstrual breast tenderness returned — something I hadn’t experienced since my 20s, before I had children. Not long after, I’d notice from time to time a pervasive edginess, a revving — an energetic feeling, but not a positive one! And I felt like I couldn’t cope as well as I used to.

When I mentioned this new set of symptoms to my primary care provider, she asked about my period and noted my age. I was 42 and still getting regular periods. It wasn’t hormonally related, she said, and offered me one medication for sleep and another for anxiety. Several months later I ran these same symptoms by my ob-gyn at my annual visit – same questions, same response.

Being told my experience wasn’t related to something biological made me question myself and what might be happening in my life to cause this. Nothing had changed. It didn’t make sense. I was determined to get to the bottom of it. I am one to share and talk to others, to question the status quo and dig into the scientific research. So that’s what I did.

Along the way, I found the work of Dr. Jerilynn Prior, an endocrinologist who founded the Centre for Menstrual Cycle and Ovulation Research (CeMCOR). Her research on perimenopause shows that many women experience changes in flow, fertility, sleep, mood, cramps, night sweats and headaches while they are still menstruating regularly. As I read more about CEMCOR’s research and about the experiences of other women in Dr. Prior’s book “Estrogen’s Storm Season,” I found validation for what I was experiencing.

I knew that I was not the only one having a hard time finding good information about perimenopause and menopause, and I wanted to find a way to share, in easy to understand language, what I had learned. I sent Dr. Prior a very long email, explaining that I thought there was an opportunity to create an online resource for women — like me — who experience the effects of changing hormones before their cycles are irregular. Lots of women do not know what to expect or what is normal, and they aren’t getting support or evidence-based information from their healthcare providers. That email was the beginning of a discussion that eventually led to the creation of Women Living Better, a resource that demystifies the menopause transition.

The site, informed by data and research, validates the wide array of physical and emotional changes women may experience. It emphasizes a key message of Dr. Prior’s: that symptoms often begin before periods are skipped and cycles become irregular. The site allows women to gather and share data with other women, so we can learn from each other’s experiences, find support, and know we are not alone.

Dr. Prior was recently in Boston, where she gave a talk about the very early perimenopause at Tufts Medical Center. * You can view a video of the event below:

I hear every day from women that are grateful to have found Women Living Better. In turn, I am grateful to Dr. Prior — for her work, her ongoing encouragement and support, and her generosity with her time and expertise.

Nina Coslov is a co-founder of Women Living Better.

* The talk was organized by Our Bodies Ourselves board member Alex Spadola, who is an ob/gyn at Tufts Medical Center. Dr. Prior has shared her expertise in several editions of “Our Bodies, Ourselves.”

6 responses to “The Very Early Perimenopause: What We Can Learn from Dr. Jerilynn Prior’s Research”

  1. My symptoms started in my late 30’s. I think in part because I never had children. I never got my doctors to take me seriously. It has been unbelievably frustrating.

    • I have had the same experience and am still dealing with it. I am now 51 and it feels like it will never end.

      I had no periods for 6 months after I had an ovary removed- I felt FANTASTIC- no bloating, pain, or insomnia, lost weight, felt very energetic.

      But, it all came back and I am miserable again. And no doctors, including gynecologists, seem to think there is any relationship of my symptoms to perimenopause.

  2. Dr. Prior’s talk was so informative and reassuring. Especially with regard to perimenopause symptoms co-occurring with REGULAR menstrual cycles. I am forwarding this page and video to my OB/GYN (who is quite forward thinking in this area) so that other patients can get more research-based information about this period (no pun intended) in our lives. (In typing this, the word perimenopause is underlined in red as a misspelling. That speaks volumes about the understanding let alone acceptance of our collective experience!)

  3. Hello! I’m suffering from such symptoms for a long time. But I would never have thought that it could be perimenopause. I have frequent night cramps, insomnia and sweating sometimes. This didn’t happen to me regularly, and I didn’t pay attention to that earlier. But when the symptoms began to become more frequent and recur from time to time, I suspected that something was wrong. I started reading information about similar symptoms at women of my age and came across your article and Dr. Prior’s video. Thank you for sharing the information! Now I know for sure what is happening to me)

  4. I hear every day from women that are grateful to have found Women Living Better. In turn, I am grateful to Dr. Prior — for her work, her ongoing encouragement and support, and her generosity with her time and expertise.

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